NB110-56973 MAPK7 / BMK1 / ERK5 antibody
see related secondary antibodiessee all 24 MAPK7 / BMK1 / ERK5 products
0.1ml g / US$ 515 no delivery possible
Quick Overview
Rabbit anti MAPK7 / BMK1 / ERK5 EP791Y
Synonyms
MAP Kinase 7, BMK1 kinase, ERK-5, ERK4, PRKM7, , Mitogen-activated protein kinase 7, Mitogen-activated protein kinase 7
Product review
Please read our product review about MAPK7 / BMK1 / ERK5 : Antibodies to MAP-Kinases.
Product Description
Rabbit anti MAPK7 / BMK1 / ERK5 EP791Y, Presentation: Purified. Product is tested for Flow cytometry ( F ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | EP791Y |
| Catalog Number | NB110-56973 |
| Swiss Prot. No. | Q13164 |
| Quantity | 0.1ml g |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-ERK5 (EP791Y) | |
| Alternate names | anti-BMK1 antibody, anti-BMK1 Kinase antibody, anti-EC 2.7.11.24 antibody, anti-ERK 4 antibody, anti-ERK 5 antibody, anti-ERK4 antibody, anti-Extracellular Signal Regulated Kinase 5 antibody, anti-MAPK 7 antibody, anti-MAPK7 antibody, anti-Mitogen Activated Protein Kinase 7 antibody, anti-PRKM 7 antibody, anti-PRKM7 antibody |
| Background | The extracellular signal-regulated kinase 5 (ERK5), also known as MAPK7 or big mitogen-activated protein kinase 1 (BMK1), is a member of the MAP kinase subfamily (1). ERK5 differs considerably from other MAPKs; it contains an unusually long carboxyl-terminal tail which might contribute to the regulation of its activity and/or localization. In response to extracellular signals, ERK5 translocates to the nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors (2). ERK5 also differs from other MAPKs in possessing a potent transcriptional activation domain which mediates protein-protein interactions with the myocyte enhancer factor 2 (MEF2) transcription factors (3). ERK5 is specifically activated by MAPK kinase 5 (MAP2K5/MEK5) and plays an important role in mammary epithelial proliferation, endothelial cell survival and normal embryonic development (4-5). |
| Immunogen | Synthetic peptide corresponding to residues in the C-terminus of Human ERK5. Swiss Num.: Q13164 |
| Format | Purification: IgG purified Purity: IgG purified BufferSystem: Constituents: 40% Glycerol, 0.5% BSA, 0.15M Sodium chloride, 50mM Tris glycine, pH 7.4 |
| Applications | flow cytometry / FACS analysis 1:30, immunoprecipitation 1:50, Western Blot 1:1,000-5,000, Immunocytochemistry 1:250-500 |
| Specificity | Species: Reacts with Mouse, Rat and Human. Not yet tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Gutkind, J. S. (2000) Science's STKE
2. Hanks, S. K., Quinn, A. M., and Hunter, T. (1988) Science 241, 42?52 3. Kasler, H. G., J. Victoria, O. Duramad, and A. Winoto. 2000. Mol. Cell. Biol. 20:8382-8389 4. Kato, Y., Tapping, R. I., Huang, S., Watson, M. H., Ulevitch, R. J., and Lee, J. D. (1998) Nature 395, 713-716 5. Esparis-Ogando, A., Diaz-Rodriguez, E., Montero, J. C., Yuste, L., Crespo, P., and Pandiella, A. (2002) Mol. Cell. Biol. 22, 270-285 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-56973 MAPK7 / BMK1 / ERK5 '.
