NB110-57146 CD321 / JAM1 / F11R antibody
see related secondary antibodiessee all 16 CD321 / JAM1 / F11R products
0.1 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti CD321 / JAM1 / F11R EP1042Y
Synonyms
F11R, JAM1, JCAM, JAM-1, Platelet adhesion molecule 1, PAM-1, Platelet F11 receptor, CD321 antigen, JAM-A, Junctional adhesion molecule 1, Junctional adhesion molecule A
Product Description
Rabbit anti CD321 / JAM1 / F11R EP1042Y, Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | EP1042Y |
| Catalog Number | NB110-57146 |
| Swiss Prot. No. | Q9Y624 |
| Quantity | 0.1 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-JAM1 (N-term) (EP1042Y) | |
| Alternate names | anti-CD321 antibody, anti-CD 321 antibody, anti-CD321 antigen antibody, anti-F11 receptor antibody, anti-F11R antibody, anti-JAM 1 antibody, anti-JAM A antibody, anti-JAM antibody, anti-JAM1 antibody, anti-JAMA antibody, anti-JCAM anti-antibody, anti-Junctional adhesion molecule A antibody, anti-KAT antibody, anti-PAM 1 antibody, anti-PAM1 antibody, anti-Platelet adhesion molecule 1 antibody, anti-Platelet adhesion molecule antibody, anti-Platelet F11 receptor antibody, anti-UNQ264/PRO301 antibody |
| Background | Junctional Adhesion Molecules (JAMs) are components and regulators of the well-characterized epithelial and endothelial tight junction. JAM is selectively concentrated at intercellular junctions of endothelial and epithelial cells of different origins. Microscopy shows that JAM codistributes with tight junction components at the apical region of the intercellular cleft. A mAb directed to JAM (BV11) was found to inhibit spontaneous and chemokine-induced monocyte transmigration through an endothelial cell monolayer in vitro. Systemic treatment of mice with BV11 mAb blocked monocyte infiltration upon chemokine administration in subcutaneous air pouches (1). The human protein shares a highly conserved structure and sequence with the murine protein. However it is distinct in that it is constitutively expressed on circulating neutrophils, monocytes, platelets and lymphocyte subsets (2). |
| Immunogen | Synthetic peptide corresponding to residues near the N-terminus of human Junctional Adhesion Molecule 1. Swiss Num.: Q9Y624 |
| Format | Purification: Ascites Purity: Ascites BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Applications | immunohistochemistry , Western Blot |
| Specificity | Species: Reacts in human, mouse, and rat. Not tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Martin-Padura I, et al. J Cell Biol 142(1):117-27, 1998
2. Williams LA, et al. Mol Immunol 36(17):1175-88. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-57146 CD321 / JAM1 / F11R'.
