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NB110-57176  M-CSF antibody

see related secondary antibodies
see all 9 M-CSF products
0.1 ml / US$ 515 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Rabbit anti M-CSF EP1179Y

Synonyms

Colony stimulating factor 1 antibody CSF 1 antibody CSF1 antibody Lanimostim antibody M CSF antibody Macrophage Colony Stimulating Factor 1 antibody Macrophage colony stimulating factor antibody MCSF antibody MGC31930 antibody,

Product Description

Rabbit anti M-CSF EP1179Y, Presentation: Aff - Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )

Properties

ApplicationsFlow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu )
PresentationAff - Purified
HostRabbit
IsotypeIgG
CloneEP1179Y
Catalog NumberNB110-57176
Quantity0.1 ml
PriceUS$ 515 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Rabbit Monoclonal anti-M-CSF (EP1179Y)
Alternate namesanti-Colony stimulating factor 1 antibody, anti-CSF 1 antibody, anti-CSF1 antibody,
anti-Lanimostim antibody, anti-M CSF antibody, anti-Macrophage Colony Stimulating Factor 1 antibody, anti-Macrophage colony stimulating factor antibody, anti-MCSF antibody, anti-MGC31930 antibody
BackgroundColony stimulating factor-1 (M-CSF) is a glycoprotein growth factor required for the proliferation and differentiation of mononuclear phagocytic cells. Findings indicate that M-CSF, under hormonal influence, plays a role in placental development and function and that steroid hormones may regulate developmental processes via their effects on the expression of tissue-specific growth factors (1). M-CSF accelerates neointimal formation after vascular injury via the SDF-1-CXCR4 system, and the inhibition of this system has therapeutic potential for the treatment of cardiovascular diseases (2). The immunosuppressor Sanglifehrin A inhibits M-CSF-dependent macrophage proliferation by arresting the G1 phase of the cell cycle but does not affect cell viability (3). Several studies have demonstrated that CSFs are closely associated with tumor progression, metastasis and invasion through autocrine or paracrine mechanism in lung cancer (4).
ImmunogenA synthetic peptide corresponding to residues on human MCSF.
Format
Purification: Ascites
Purity: Ascites
BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA.
ApplicationsELISA , immunohistochemistry , immunoprecipitation , Western Blot , Immunocytochemistry
Specificity
Species: Reacts in human. Does not react in mouse or rat. Not tested in other species.
StorageAliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
References1. Pollard JW, et al. Nature 330(6147):484-6, 1987.
2. Shiba Y, et al. Arterioscler Throm Vasc Biol, 27(2):283-
9,006
3. Sanchez-Tillo E, et al. Eur J Immunol. 36(9):2515-24, 2006
4. Uemura Y, et al. Int J Mol Med 18(2):365-73, 2006.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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