NB110-57239 NAK/TBK1 (N-term) antibody
see related secondary antibodies
0.1 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti NAK/TBK1 (N-term) EP611Y
Synonyms
EC 2.7.11.1 antibody FLJ11330 antibody NAK antibody NF kappa B activating kinase antibody NF kB activating kinase antibody Serine/threonine protein kinase TBK 1 antibody Serine/threonine protein kinase TBK1 antibody T2K antibody TANK antibody TANK binding,
Product Description
Rabbit anti NAK/TBK1 (N-term) EP611Y, Presentation: Aff - Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Clone | EP611Y |
| Catalog Number | NB110-57239 |
| Quantity | 0.1 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Monoclonal anti-NAK/TBK1 (N-term) (EP611Y) | |
| Alternate names | anti-EC 2.7.11.1 antibody, anti-FLJ11330 antibody, anti-NAK antibody, anti-NF kappa B activating kinase antibody, anti-NF kB activating kinase antibody, anti-Serine/threonine protein kinase TBK 1 antibody, anti-Serine/threonine protein kinase TBK1 antibody, anti-T2K antibody, anti-TANK antibody, anti-TANK binding kinase 1 antibody, anti-TBK 1 antibody, anti-TBK1 antibody, anti-TRAF 2 antibody, anti-TRAF2 antibody, anti-TRIF antibody |
| Background | NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor−associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family (1). Similar to IKK alpha and beta (2), NAK induces IkB degradation and NF-kB activity. NAK is activated by phorbol ester tumour promoters and growth factors, whereas catalytically inactive NAK specifically inhibits activation of NF-kB by protein kinase C-epsilon (PKCepsilon). NAK specifically phosphorylates IkB alpha on Serine 36 and NFkB subunit RelA (p65) on Serine 536 (3). NAK is also known to interact with TANK, TRAF-2 and TRIF (4). |
| Format | BufferSystem: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
| Applications | immunohistochemistry, immunoprecipitation, Western Blot, Immunocytochemistry |
| Specificity | Species: Reacts in human, mouse, and rat. Not tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Pomerantz, J. L.; Baltimore, D. : EMBO J. 18: 6694-6704, 1999.
2. Karin, M. (1999) J. Biol. Chem. 274, 27339?27342 3. Tojima, Y., Fujimoto, A., Delhase, M., Chen, Y., Hatakeyama, S., Nakayama, K., Kaneko, Y., Nimura, Y., Motoyama, N., Ikeda, K., Karin, M., and Nakanishi, M. (2000) Nature 404, 778?782 4. Nomura, F., Kawai, T., Nakanishi, K., and Akira, S. (2000) Genes Cells 5, 191-202 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB110-57239 NAK/TBK1 (N-term)'.
