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NB110-60521SS  BAP1 antibody

see related secondary antibodies
see all 3 BAP1 products
0.025 ml / US$ 295 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Mouse anti BAP1 1G8

Synonyms

anti-Ubiquitin carboxyl-terminal hydrolase BAP1 antibody, anti-EC 3.4.19.12 antibody, anti-BRCA1-associated protein 1 antibody, anti-Cerebral protein 6 antibody, anti-BAP-1 antibody,

Product Description

Mouse anti BAP1 1G8, Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )

Properties

ApplicationsWestern blot / Immunoblot ( WB )
ReactivityHuman ( Hu )
PresentationPurified
HostMouse
IsotypeIgG1
Clone1G8
Catalog NumberNB110-60521SS
Quantity0.025 ml
PriceUS$ 295 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Mouse Monoclonal anti-BAP1 (1G8), Sample Size
Alternate namesanti-Ubiquitin carboxyl-terminal hydrolase BAP1 antibody, anti-EC 3.4.19.12 antibody, anti-BRCA1-associated protein 1 antibody, anti-Cerebral protein 6 antibody, anti-BAP-1 antibody
BackgroundMutations within the BRCA1 gene, localized to chromosome 17q, are believed to account for approximately 45% of families with increased incidence of both early-onset breast cancer and ovarian cancer. The BRCA1 gene is expressed in numerous tissues, including breast and ovary, and encodes a predicted protein of 1863 amino acids. This protein contains a RING domain near the N-terminus and appears to encode a tumor suppressor. BARD1 (BRCA1-associated RING domain protein 1) and BAP1 (BRCA1-associated protein 1) have both been shown to bind to the N-terminus of BRCA1 and are potential mediators of tumor suppression. BARD1 contains an N-terminal RING domain and three tandem ankyrin repeats. The C-terminus of BARD1 contains a region with sequence homology to BRCA1, termed the BRCT domain. BAP1 is a ubiquitin hydrolase and has been shown to enhance BRCA1-mediated cell growth suppression.
ImmunogenFull-length human BAP1 protein expressed and purified from E.coli. [Uniprot# Q92560]
Format
Purification: protein G purified
Purity: protein G purified
BufferSystem: Tris-glycine, 150mM NaCl
ApplicationsWB
Specificity
Species: Human. Other species have not been tested.
References1. Jensen, DE, et al. Oncogene. 16: 1087-1112 (1998)

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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