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NB120-2875  Junctional Sarcoplasmic Reticulum antibody

see related secondary antibodies
see all 4 Junctional Sarcoplasmic Reticulum products
0.1 ml / US$ 455 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Mouse anti Junctional Sarcoplasmic Reticulum VF1c

Product Description

Mouse anti Junctional Sarcoplasmic Reticulum VF1c, Presentation: Ascites. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )

Properties

ApplicationsImmunofluorescence ( IF ), Western blot / Immunoblot ( WB )
ReactivityRabbit ( Rb ), Genua Pig ( GP )
PresentationAscites
HostMouse
IsotypeIgG1
CloneVF1c
Catalog NumberNB120-2875
Quantity0.1 ml
PriceUS$ 455 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Mouse Monoclonal anti-Junctional Sarcoplasmic Reticulum (VF1c)
BackgroundThe junction between the transverse tubules (T-tubules) and the sarcoplasmic reticulum (SR) of skeletal muscle is called the triad. At the triad, dihydropyridine receptors (DHPR?s) of the T-tubule serve as voltage sensors in excitation-contraction coupling, while ryanodine receptors (RyR?s), the calcium release channels, exist in the membrane of the terminal cisternae of the SR. It is thought that during slow phase depolarization of the T-tubule, a third protein, triadin (95 kDa) transmits electrochemical signals to the SR through direct interaction with both DHPR?s and RyR?s. Another skeletal muscle specific 90 kDa protein has also been localized to the this junction. This protein is phosphorylated by an intrinsic protein kinase in triads suggesting that it may play an important regulatory or structural role in the skeletal muscle triad junction.
ImmunogenRabbit skeletal muscle triads.
Format
Purification: Ascites
Purity: Ascites
BufferSystem: PBS with 0.05% sodium azide
ApplicationsIF, WB
Specificity
Species: Cross-reacts strongly with Rabbit and Guinea pig, moderately with Dog and Rat and weakly with Mouse.Not yet tested in other species.
ReferencesThis product has been used in:Campbell KP et al. Identification and characterization of the high affinity [3H]ryanodine receptor of the junctional sarcoplasmic reticulum Ca2+ release channel. J Biol Chem 262:6460-3 (1987). General / background references:Guo W et al. Characterization and ultrastructural localization of a novel 90-kDa protein unique to skeletal muscle junctional sarcoplasmic reticulum. J Biol Chem 269:28359-65 (1994).

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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