NB300-123 mGluR1a / GRM1a antibody
see related secondary antibodiessee all 9 mGluR1a / GRM1a products
0.1 ml / US$ 485 no delivery possible
Quick Overview
Rabbit anti mGluR1a / GRM1a
Synonyms
Metabotropic glutamate receptor 1a, mGluR1 alpha, GRM1 alpha, GPRC1A, , Glutamate receptor metabotropic 1 alpha, Glutamate receptor metabotropic 1a, mGluR1-alpha, GRM1-alpha
Product review
Please read our product review about mGluR1a / GRM1a : Metabotropic Glutamate Receptor Antibodies.
Product Description
Rabbit anti mGluR1a / GRM1a , Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Western blot / Immunoblot ( WB ) |
| Reactivity | Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NB300-123 |
| Swiss Prot. No. | P23385 |
| Quantity | 0.1 ml |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB300-123.pdf |
Datasheet Extract
| Rabbit Polyclonal anti-Glutamate receptor 1a (metabotropic) | |
| Background | Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainate receptors that are involved in the fast excitatory synaptic transmission. Glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors, stimulate phospholipase C as revealed by an increase in phosphoinositide turnover, and Ca2+ release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors include mGluR2 and mGluR3. |
| Immunogen | NB 300-123 was raised against a synthetic peptide corresponding to amino acids 1116-1130 of rat mGluR1a, with an N-appended
lysine coupled to thyroglobulin using glutaraldehyde. Swiss Num.: P23385 |
| Format | Purification: Affinity purified Purity: Affinity purified |
| Applications | Western Blot 1:1000+, Immunohistochemistry-Frozen 1:500-1:1000+, Immuno-EM |
| Specificity | Species: NB 300-123 reacts with rat mGluR1a. Other species have not been tested, but should work with most mammalian species due to sequence homology. This antibody does not cross-react with other splice variants or mGluR5. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Pin, j-P, Duvoisin, R. Review: Neurotransmitter receptor 1: The metabotropic glutamate receptors: structure and function. Neuropharmacology. 34: 1-26, 1995. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB300-123 mGluR1a / GRM1a '.
