NB300-124 mGluR2/3 antibody
see related secondary antibodiessee all 8 mGluR2/3 products
0.1 ml / US$ 485 no delivery possible
Quick Overview
Rabbit anti mGluR2/3
Synonyms
Metabotropic glutamate receptor 2/3, GRM2, GRM3, , Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 3, mGlu 2, mGlu 3, mGlu2
Product review
Please read our product review about mGluR2/3: Metabotropic Glutamate Receptor Antibodies.
Product Description
Rabbit anti mGluR2/3 , Presentation: Aff - Purified. Product is tested for Frozen sections ( C ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NB300-124 |
| Swiss Prot. No. | P31421 |
| Quantity | 0.1 ml |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB300-124.pdf |
Datasheet Extract
| Rabbit Polyclonal anti-Glutamate receptor 2/3 (metabotropic) | |
| Alternate names | Anti-G protein coupled receptor family C group 1 member B antibody; Anti-G protein coupled receptor family C group 1 member C antibody; Anti-GLUR 2 antibody; Anti-GLUR 3 antibody; Anti-GLUR2 antibody; Anti-GLUR3 antibody; Anti-Glutamate receptor homolog antibody; Anti-Glutamate receptor metabotropic 2 antibody; Anti-Glutamate receptor metabotropic 3 antibody; Anti-GPRC1B antibody; Anti-GPRC1C antibody; Anti-GRM2 antibody; Anti-GRM3 antibody; Anti-Metabotropic glutamate receptor 2 antibody; Anti-Metabotropic glutamate receptor 3 antibody; Anti-mGlu 2 antibody; Anti-mGlu 3 antibody; Anti-mGlu2 antibody; Anti-mGlu3 antibody; Anti-MGLUR2 antibody; Anti-MGLUR3 antibody; Anti-mGluR7 antibody
|
| Concentration | 113 mg/ml |
| Background | Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainate receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors, stimulate phospholipase C as revealed by an increase in phosphoinositide turnover, and Ca2+ release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3. |
| Immunogen | This antibody was raised against a synthetic peptide corresponding to the 13 c-terminus amino acids of mGluR2/3 with an N-appended lysine coupled to thyroglobulin using glutaraldehyde. Swiss Num.: P31421 |
| Format | Purification: Affinity purified Purity: Affinity purified BufferSystem: 200 mM Tris-Glycine (pH 7.5) |
| Applications | immunoprecipitation , Western Blot 1:1000, Immunohistochemistry-Frozen 1:500 |
| Specificity | Species: NB 300-124 reacts with rat mGluR2/3. Other species have not been tested, but should work with most mammalian species due to sequence homology. |
| Storage | Refrigerate until working aliquots are established. For safest long-term storage, maintain aliquots at -80 degrees or at -20 degrees. Avoid repeated freeze-thaw cycles. |
| References | 1. Pin, j-P, Duvoisin, R. Review: Neurotransmitter receptor 1: The metabotropic glutamate receptors: structure and function. Neuropharmacology. 34: 1-26, 1995. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB300-124 mGluR2/3'.
