NB300-502 Early endosome antigen 1 antibody
see related secondary antibodiessee all 15 Early endosome antigen 1 products
0.1 mg / US$ 485 no delivery possible
Quick Overview
Rabbit anti Early endosome antigen 1
Synonyms
EEA1, ZFYVE2, Endosome-associated protein p162, Zinc finger FYVE domain-containing protein 2
Product Description
Rabbit anti Early endosome antigen 1 , Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Canine ( Can ), Hamster ( Hst ), Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | NB300-502 |
| Swiss Prot. No. | Q15075 |
| Quantity | 0.1 mg |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Rabbit Polyclonal anti-EEA1 | |
| Alternate names | anti-Early Endosomal Antigen 1 antibody, anti-EEA 1 antibody |
| Concentration | 1 mg/ml |
| Background | Early endosomal antigen 1 (EEA1) is a 162 kDa membrane bound protein component specific to the early endosome and is essential for fusion between early endocytic vesicles. Early endosomes are cytoplasmic compartments which fuse with endocytic vesicles for redistribution of extracellular compounds to alternate destinations. Zinc-finger-like domains, reminiscent of those found in nucleic acid binding proteins, are located in the amino and carboxyl-terminal domains of EEA1. The carboxyl-terminal zinc-finger-like-domain is conserved in several other non-nuclear proteins, some of which are also involved in intracellular protein trafficking. In addition, this domain is an authentic zinc-binding domain and is critical to the intracellular localization of EEA1. Membrane association of EEA1 has been shown dependent on phosphatidyl 3-kinase activity, inhibitors of which cause EEA1 to dissociate from early endosomes. |
| Immunogen | Synthetic peptide with sequence TPSSKKPVRVCDACFNDLQG, corresponding to amino acids 1391-1410 of Human EEA1. Swiss Num.: Q15075 |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: PBS with 1 mg/ml BSA containing 0.05% sodium azide |
| Applications | immunofluorescence , immunoprecipitation , Western Blot |
| Specificity | Species: Cross-reacts with Human, Xenopus laevis (see review), Dog, Hamster, Mouse and Rat. Not yet tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | Mills IG et al. Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes. Curr Biol 8:881-4 (1998). |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB300-502 Early endosome antigen 1 '.
