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NB300-557  CAMK2A / CaMK II alpha antibody

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see all 39 CAMK2A / CaMK II alpha products
0.1 ml / US$ 485 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Mouse anti CAMK2A / CaMK II alpha 6G9

Synonyms

CAMKA, KIAA0968, kinase II subunit alpha, CaMK-II subunit alpha, , Calcium/calmodulin-dependent protein kinase type II alpha chain

Product review
Please read our product review about CAMK2A / CaMK II alpha : Antibodies to Calmodulin and CaM-kinases.

Product Description

Mouse anti CAMK2A / CaMK II alpha 6G9, Presentation: Ig Fraction. Product is tested for Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )

Properties

ApplicationsImmunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
ReactivityRat ( Rt )
PresentationIg Fraction
HostMouse
IsotypeIgG1
Clone6G9
Catalog NumberNB300-557
Swiss Prot. No.P11275
Quantity0.1 ml
PriceUS$ 485 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/p ...

Datasheet Extract

Mouse Monoclonal anti-CaM Kinase II (6G9)
Alternate namesanti-alpha CaMKII antibody, anti-Calcium / Calmodulin Dependent Protein Kinase II G antibody, anti-Calcium calmodulin dependent protein kinase CaM kinase II alpha antibody, anti-Calcium calmodulin dependent protein kinase II alpha-B subunit antibody, anti-Calcium calmodulin dependent protein kinase type II alpha chain antibody, anti-Calcium calmodulin dependent protein kinase type II beta chain antibody, anti-Calcium/calmodulin dependent protein kinase II alpha antibody, anti-Calcium/calmodulin dependent protein kinase type II alpha chain antibody, anti-CaM kinase II alpha chain antibody, anti-CaM kinase II alpha subunit antibody, anti-CaM kinase II beta chain antibody, anti-CaM kinase II beta subunit antibody, anti-CaM kinase II delta chain antibody, anti-CaM kinase II delta subunit antibody, anti-CAM2 antibody, anti-CaMK II alpha subunit antibody, anti-CaMK II beta subunit antibody, anti-CaMK II delta subunit antibody, anti-Camk2a antibody, anti-CAMK2B antibody, anti-CAMK2D antibody, anti-CAMKA antibody, anti-CAMKB antibody, anti-KIAA0968 antibody, anti-MGC123320 antibody, anti-MGC139375 antibody, anti-PK2CDD antibody, anti-PKCCD antibody, anti-Proline rich calmodulin dependent protein kinase antibody, anti-zgc:123320 antibody
BackgroundCaM kinase II, in a calcium and calmodulin dependent manner, phosphorylates many different brain substrates including synapsin I, tryptophan hydroxylase, tyrosine hydroxylase and nitric oxide synthase thereby performing regulatory functions associated with increases in intracellular free calcium. CaM kinase II is particularly abundant in the hippocampus and forebrain where it comprises ~1% of total protein. Within the neuron, CaM kinase II is a major component of the postsynaptic density fraction accounting for as much as 30% of total protein in the post synaptic density (PSD) region. Autophosphorylation of threonine-286 occurs after calcium/calmodulin activation and can enable CaM kinase II to remain active independent of free calcium. Autophosphorylation of CaM kinase II in hippocampal neurons, which results in relatively high levels of kinase activity even at basal calcium concentrations, may allow for both upward and downward regulation as opposed to simply on/off regulation.
ImmunogenPartially purified rat CaM kinase II
Swiss Num.: P11275
Format
Purification: IgG purified
Purity: IgG purified
BufferSystem: PBS
Applicationsimmunohistochemistry Assay dependent, immunofluorescence 1:100, immunoprecipitation Assay dependent, Western Blot 1:2,000
Specificity
Species: Cross-reacts with Rat.Not yet tested in other species.
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles.
ReferencesThis product has been used in:Erondu NE & Kennedy MB Regional distribution of type II Ca2+/calmodulin-dependent protein kinase in rat brain. J Neurosci 5:3270-7 (1985). General / background references:Zhang W et al. Citron binds to PSD-95 at glutamatergic synapses on inhibitory neurons in the hippocampus. J Neurosci 19:96-108 (1999). Easom RA et al. Correlation of the activation of Ca2+/calmodulin-dependent protein kinase II with the initiation of insulin secretion from perifused pancreatic islets. Endocrinology 138:2359-64 (1997).

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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