NB300-568 N-CoR 2 / SMRT antibody
see related secondary antibodiessee all 12 N-CoR 2 / SMRT products
0.1 mg / US$ 485 no delivery possible
Quick Overview
Mouse anti N-CoR 2 / SMRT 1212
Product Description
Mouse anti N-CoR 2 / SMRT 1212, Presentation: Ig Fraction. Product is tested for Frozen sections ( C ), ChIP assay ( ChIP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), ChIP assay ( ChIP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Ig Fraction |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | 1212 |
| Catalog Number | NB300-568 |
| Quantity | 0.1 mg |
| Price | US$ 485 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Mouse Monoclonal anti-SMRT (1212) | |
| Alternate names | anti-NCoR2 antibody, anti-CTG 26 antibody, anti-CTG repeat protein 26 antibody, anti-CTG26 antibody, anti-N CoR2 antibody, anti-NCoR 2 antibody, anti-Nuclear Receptor Co-Repressor 2 antibody, anti-Silencing Mediator for Retanoid and Thyroid Hormone Receptors antibody, anti-SMAP270 antibody, anti-SMRT antibody, anti-SMRTE antibody, anti-SMRTE tau antibody, anti-T3 receptor-associating factor antibody, anti-Thyroid retinoic acid receptor associated corepressor antibody, anti-Thyroid- retinoic-acid-receptor-associated corepressor antibody, anti-TRAC 1 antibody, anti-TRAC antibody, anti-TRAC1 antibody |
| Background | Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing Mediator of Retinoic acid and Thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity. |
| Immunogen | Synthetic peptide: CGGA-SASDPHREKTQ, corresponding to amino acids 994-1005 of Human NCoR 2. |
| Format | Purification: IgG purified Purity: IgG purified BufferSystem: PBS, 1 mg/ml BSA |
| Applications | chromatin immunoprecipitation , immunohistochemistry 1:50, Western Blot 1:250 |
| Specificity | Species: Cross-reacts with Human.Does not cross-react with Rat.Not yet tested in other species. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | General / background references:Hudelist G et al. Expression of sex steroid receptors and their co-factors in normal and malignant breast tissue: AIB1 is a carcinoma-specific co-activator. Breast Cancer Res Treat 78:193-204 (2003). |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB300-568 N-CoR 2 / SMRT'.
