NB400-107 LCAT antibody
see related secondary antibodiessee all 7 LCAT products
0.1 ml / US$ 435 no delivery possible
Quick Overview
Rabbit anti LCAT
Product Description
Rabbit anti LCAT , Presentation: Serum. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Serum |
| Host | Rabbit |
| Catalog Number | NB400-107 |
| Quantity | 0.1 ml |
| Price | US$ 435 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet | view  NB400-107.pdf |
Datasheet Extract
| Rabbit Polyclonal anti-LCAT | |
| Alternate names | anti-lecithin-cholesterol acyltransferase antibody |
| Background | Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP) it is also responsible for a significant proportion of VLDL and LDL cholesteryl esters. LCAT, through the esterification of cholesterol, plays a role in the reverse cholesterol transport pathway by facilitating the net movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency results in low levels of plasma HDL, whereas a transgenic overexpression of LCAT results in increased plasma HDL concentrations. |
| Immunogen | Carboxy-terminal histidine-tagged human recombinant LCAT purified from the medium of CHO cells overexpressing human LCAT cDNA. |
| Format | Purification: Whole antisera Purity: Whole antisera BufferSystem: serum with 0.01% sodium azide |
| Applications | Western Blot 1:1000 |
| Specificity | Species: Human LCAT. Reactivity with mouse LCAT is poor. Other species have not been tested. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | 1. Chisholm, J., et al. Characterization of C-terminal histidine-tagged human recombinant lecithin:cholesterol acyltransferase. Journal of Lipid Research. 40: 1512-1519, 1999.
2. Furbee, J.W., et al. In vivo contribution of LCAT to apolipoprotein B lipoprotein Cholesteryl esters in LDL receptor and apolipoprotein E knockout mice. Journal of Lipid Research. 43(3): 428-437, 2002. 3. Furbee, J.W., et al. Lecithin:cholesterol acyltransferase deficiency increases arteriosclerosis in the low density lipoprotein receptor and apolipoprotein E knockout mice. J. Biol. Chem. 277(5): 3511-3519, 2002. 1. Matsuura, F., Wang, N., Chen, W., Jiang, X.-C., and Tall, A. R. (2006) HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway, 116, 1435-1442. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB400-107 LCAT'.
