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NB500-336  Lck antibody

see related secondary antibodies
see all 59 Lck products
0.1 mg / US$ 465 no delivery possible
please contact the manufacturer
Novus Biologicals
Littleton, CO, USA
www.novus-biologicals.com

Quick Overview

Mouse anti Lck LCK-01

Synonyms

anti-Lck p56 antibody, anti-Lymphocyte Specific Protein Tyrosine Kinase antibody, anti-Membrane associated protein tyrosine kinase antibody, anti-Oncogene lck antibody, anti-P56 LCK antibody, anti-Proto oncogene tyrosine protein kinase LCK antibody, anti-T cell specific protein tyrosine kinase antibody,

Product Description

Mouse anti Lck LCK-01, Presentation: Aff - Purified. Product is tested for Flow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )

Properties

ApplicationsFlow cytometry ( F ), Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu )
PresentationAff - Purified
HostMouse
IsotypeIgG1
CloneLCK-01
Catalog NumberNB500-336
Quantity0.1 mg
PriceUS$ 465 no delivery possible
DeliveryNot USA/Canada
ManufacturerNovus Biologicals Inc.
DatasheetPDF-Download
http://www.novusbio.com/d ...

Datasheet Extract

Mouse Monoclonal anti-Lck (LCK-01)
Alternate namesanti-Lck p56 antibody, anti-Lymphocyte Specific Protein Tyrosine Kinase antibody, anti-Membrane associated protein tyrosine kinase antibody, anti-Oncogene lck antibody, anti-P56 LCK antibody, anti-Proto oncogene tyrosine protein kinase LCK antibody, anti-T cell specific protein tyrosine kinase antibody
BackgroundLck (p56lck), a member of the Src family of non-receptor tyrosine protein kinases, is expressed predominantly in T cells. Lck function is critical both for T cell development in the thymus and activation of mature T cells in the periphery by antigen. The activity of Lck is known to be regulated by phosphorylation of two conserved tyrosine residues, Tyr-505 (equivalent to Tyr-529 in c-Src) and Tyr-394 (equivalent to Tyr-418 in c-Src).
ImmunogenSynthetic peptide, corresponding to amino acids 22-36 of Human Lck p56.
Format
Purification: Affinity purified
Purity: Affinity purified
BufferSystem: 15mM Sodium Azide in PBS. pH 7.4
ApplicationsFACS, ICC, IP, WB
Specificity
Species: Cross-reacts with Human. Does not react with Mouse. Not yet tested in other species.
StorageStore at +4 degrees C for 3 months. For long-term storage aliquot and store at -20 degrees C. Avoid freeze/thaw cycles.
References1. Romagnoli P et al. A potential role for protein tyrosine kinase p56(lck) in rheumatoid arthritis synovial fluid T lymphocyte hyporesponsiveness. Int Immunol 13:305-12 (2001).
2. Cebecauer M et al. Incorporation of leucocyte GPI-anchored proteins and protein tyrosine kinases into lipid-rich membrane domains of COS-7 cells. Biochem Biophys Res Commun 243:706-10 (1998).

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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