NB600-1384H LC3B antibody
see related secondary antibodiessee all 5 LC3B products
0.1 ml / no delivery possible
Quick Overview
Rabbit anti LC3B
Synonyms
anti-Microtubule-associated protein 1 light chain 3 beta antibody; anti-MAP1A/MAP1B LC3 B antibody; anti-MAP1A/1B light chain 3 B antibody; anti-MAP1 light chain 3-like protein 2 antibody; anti-Autophagy-related protein LC3 B antibody; anti-Autophagy-related ubiquitin-like modifier LC3 B antibody; anti-LC3-II antibody,
Product Description
Rabbit anti LC3B , Presentation: Serum. Product is tested for Frozen sections ( C ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Immunofluorescence ( IF ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Serum |
| Host | Rabbit |
| Catalog Number | NB600-1384H |
| Quantity | 0.1 ml |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-LC3B , conjugated to HRP | |
| Alternate names | anti-Microtubule-associated protein 1 light chain 3 beta antibody; anti-MAP1A/MAP1B LC3 B antibody; anti-MAP1A/1B light chain 3 B antibody; anti-MAP1 light chain 3-like protein 2 antibody; anti-Autophagy-related protein LC3 B antibody; anti-Autophagy-related ubiquitin-like modifier LC3 B antibody; anti-LC3-II antibody |
| Background | Autophagy is a process of intracellular bulk degradation in which cytoplasmic components, including organelles, are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. During macroautophagy, the sequestering vesicles, termed autophagosomes, fuse with the lysosome or vacuole resulting in the delivery of an inner vesicle (autophagic body) into the lumen of the degradative compartment. There are 16 proteins participating in the autophagy pathway in humans. The autophagy protein LC3, a mammalian homologue of Atg8, was originally identified as microtubule-associated protein 1 light chain 3. It is a component of both the MAP1A and MAP1B microtubule-binding domains and the heavy-chain independent regulation of LC3 expression may modify MAP1 microtubule-binding activity during development. LC3 is the only known mammalian protein identified that stably associates with the autophagosome membranes. LC3-I is cytosolic and LC3-II is membrane bound and enriched in the autophagic vacuole fraction. The detection of LC3-I to LC3-II conversion is a useful and sensitive marker for distinguishing autophagy in mammalian cells. |
| Immunogen | A synthetic peptide made to the N-terminal region of the human LC3, isoform B protein. |
| Format | Purification: Whole antisera Purity: Whole antisera |
| Applications | immunohistochemistry 1:2000,,immunofluorescence 1:2000,,Western Blot 1:3000,,Immunocytochemistry 1:2000 |
| Specificity | Species: This antibody reacts with the human and mouse proteins. Other species have not been tested. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| References | Hiroshi Aoki, Yasunari Takada, Seiji Kondo, Raymond Sawaya, Bharat Aggarwal, and Yasuko Kondo, Evidence That Curcumin Suppresses the Growth of Malignant Gliomas In Vitro and In Vivo Through Induction of Autophagy: Role of Akt and ERK Signaling Pathway, Mol Pharmacol. 2007 Mar 29; [Epub ahead of print] |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NB600-1384H LC3B'.