NB600-563 S100A1 / Protein S100-A1 antibody
see related secondary antibodiessee all 21 S100A1 / Protein S100-A1 products
0.5 ml / US$ 445 no delivery possible
Quick Overview
Mouse anti S100A1 / Protein S100-A1 4C4.9
Synonyms
S100 Calcium-binding protein A1, S100A, S-100 protein alpha chain, , S-100 protein alpha subunit
Product review
Please read our product review about S100A1 / Protein S100-A1 : Antibodies to S100 Family.
Product Description
Mouse anti S100A1 / Protein S100-A1 4C4.9, Presentation: Purified. Product is tested for Frozen sections ( C ), Paraffin Sections ( P )
Properties
| Applications | Frozen sections ( C ), Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Rat ( Rt ), Mouse ( Ms ), Bovine ( Bov ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG2a |
| Clone | 4C4.9 |
| Catalog Number | NB600-563 |
| Swiss Prot. No. | P23297 |
| Quantity | 0.5 ml |
| Price | US$ 445 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/p ... |
Datasheet Extract
| Mouse Monoclonal anti-S100 (4C4.9) | |
| Alternate names | anti-Bpb antibody, anti-NEF antibody, anti-S 100 PROTEIN BETA CHAIN antibody, anti-S100 alpha antibody, anti-S100 calcium binding protein A1 antibody, anti-S100 calcium binding protein beta neural antibody, anti-S100 protein alpha chain antibody, anti-S100 protein alpha polypeptide antibody, anti-S100 protein beta polypeptide neural antibody, anti-S100A antibody, anti-S100a1 antibody, anti-S100B antibody |
| Background | S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. Immunoreactive S100 protein localizes in the cytoplasm and nuclei of astrocytes, Schwann's cells, ependymomas and astrogliomas. Ganglion cells do not stain for S100 protein. S100 can be detected in almost all benign naevi and malignant melanocytic tumours of the skin, and in Langerhans cells in the skin.
|
| Immunogen | Purified bovine brain S100 protein. Swiss Num.: P23297 |
| Format | Purification: IgG purified Purity: IgG purified BufferSystem: Contains Sodium Azide |
| Applications | immunohistochemistry-Fr, immunohistochemistry-P |
| Specificity | Species: Cross-reacts with Human, Rat, Mouse and Cow. Not yet tested in other species. |
| Storage | Store at 4C. Do not freeze. |
| References | General / background references:Joshi MG et al. The role of immunocytochemical markers in the differential diagnosis of proliferative and neoplastic lesions of the breast. Mod Pathol 9:57-62 (1996). |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
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