NSB214 RAC1 + Cdc42 antibody
see related secondary antibodiessee all 2 RAC1 + Cdc42 products
0.1 ml / US$ 515 no delivery possible
Quick Overview
Rabbit anti RAC1 + Cdc42
Synonyms
anti-Cell Division Cycle 42 antibody, anti-G25K antibody, anti-GTP Binding Protein antibody, anti-Rac A antibody, anti-RacA antibody, anti-Ras Related C3 Botulinum Toxin Substrate 1 antibody, anti-Rho Family Small GTP Binding Protein antibody, anti-TC-25 antibody,
Product Description
Rabbit anti RAC1 + Cdc42 , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | NSB214 |
| Quantity | 0.1 ml |
| Price | US$ 515 no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Novus Biologicals Inc. |
| Datasheet |  http://www.novusbio.com/d ... |
Datasheet Extract
| Rabbit Polyclonal anti-RAC1 + Cdc42 [Ser71] | |
| Alternate names | anti-Cell Division Cycle 42 antibody, anti-G25K antibody, anti-GTP Binding Protein antibody, anti-Rac A antibody, anti-RacA antibody, anti-Ras Related C3 Botulinum Toxin Substrate 1 antibody, anti-Rho Family Small GTP Binding Protein antibody, anti-TC-25 antibody |
| Background | RAC, Cdc 42 and Rho A, B, and C are members of a small RhoGTPase family that bind and hydrolyze GTP. GTP bound RAC 1 and cdc 42 play a pivotal role in controlling cell shape, adhesion, growth and transformation. Active Rac 1 is implicated in regulating serum response element (SRE), NFAT 1 and nuclear factor kappa B (NF kappa B) transcription activities. Activated RAC 1 and Cdc 42 bind and activate PAK 1, which in turn activates key downstream signaling proteins including MEKK 1 and JNK. RAC 1 and Cdc 42 are phosphorylated on serine 71, a putative Akt site located between the protein binding domain and GTP binding domain. Phosphorylation of RAC 1 on serine 71 regulates its GTP binding and GTPase activity. |
| Immunogen | Synthetic phospho peptide (Human) containing serine 71. The sequence is conserved in human and mouse RAC 1, 2, and 3, and Cdc 42 human, mouse, rat, dog and frog. |
| Format | Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: Constituents: 50% Glycerol, PBS, 1mg/ml BSA (IgG, protease free). pH |
| Applications | WB |
| Specificity | Species: Cross-reacts with Human. Expected to cross-react with Mouse (100% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| References | General / background references:Servitja JM et al. Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src. J Biol Chem 278:34339-46 (2003). |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'NSB214 RAC1 + Cdc42'.
