PA1134 Thrombopoietin antigen
see all 19 Thrombopoietin products
2 µg / US$ 225
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse Thrombopoietin
Product Description
Mouse Thrombopoietin
Properties
| Presentation | Purified |
| Species | Mouse |
| Purity | >98% |
| Source | E. coli |
| Molecular Weight | 19 kD |
| Catalog Number | PA1134 |
| Quantity | 2 µg |
| Price | US$ 225 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA1134.pdf |
Datasheet Extract
| Alternate names | Megakaryocyte colony-stimulating factor, Myeloproliferative leukemia virus oncogene ligand, C-mpl ligand, ML, Megakaryocyte growth and development factor, MGDF, TPO, MKCSF, MPLLG, MGC163194, THPO |
| Concentration | 1,0 mg/ml |
| Background | Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidneyt hat regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets. |
| Source | Escherichia Coli |
| Format | State: Lyophilized purified protein (sterile filtered) Purity: Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. Reconstitution: Restore in sterile 18Mohm-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Description | Thrombopoietin Mouse Recombinant produced in E.Coli is a single, non-glycosylated soluble polypeptide chain containing 174 amino acids which comprises the receptor binding domain of the Mpl-ligand protein.
The TPO is purified by proprietary chromatographic techniques. AASequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Pro-Val-Ala-Pro. Biological Activity: The ED50 as determined by the dose-dependant stimulation of MO7e cells is < 1 ng/ml. Specific Activity: 1 x 10e6 IU/mg Molecular weight: 18704 Dalton |
| Storage | Prior to reconstitution stable at RT for 3 weeks.
Following reconstitution store the protein undiluted at 2-8°C for one week or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Shelf life: one year from despatch. |
