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PA1195XC  Octreotide antigen


see all 3 Octreotide products
25 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Human Octreotide

Product Description

Human Octreotide

Properties

PresentationPurified
SpeciesHuman
Purity>98%
SourceSynthetic
Catalog NumberPA1195XC
Quantity25 mg
Priceplease contact our distributor
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
PA1195XC.pdf

Datasheet Extract

Concentration1.0 mg/ml
BackgroundOctreotide acetate is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. It inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone.
Format
State: Sterile Filtered White lyophilized (freeze-dried) powder.
Purity: Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
BufferSystem: Octreotide was lyophilized from a concentrated solution with no additives.
Reconstitution: It is recommended to reconstitute the lyophilized Octreotide in sterile 18M?-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
DescriptionSynthetic Human Octreotide is a single, non-glycosylated, polypeptide chain containing 8 amino acids, having a molecular formula of C49H66N10O10S2 .
Octreotide is purified by proprietary chromatographic techniques.
AASequence: The sequence was determined to be H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol.
Molecular weight: 1019.26 Dalton
StorageLyophilized Octreotide although stable at room temperature, should be stored desiccated below 0°C. Reconstituted Octreotide is best stored refrigerated at 4°C. Please avoid freeze-thaw cycles.
References1. The role of octreotide versus placebo in the prevention of post-ERCP pancreatitis.
Hepatogastroenterology 2007 Jan-Feb;54(73):250-3
2. Octreotide for esophageal variceal bleeding treated with endoscopic sclerotherapy: a randomized, placebo-controlled trial. Hepatogastroenterology 2007 Jan-Feb;54(73):195-200
3. 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT. J Nucl Med 2007 Apr;48(4):508-18
4. Octreotide inhibits hepatic cystogenesis in a rodent model of polycystic liver disease by reducing cholangiocyte adenosine 3',5'-cyclic monophosphate. Gastroenterology 2007 Mar;132(3):1104-16
5. Administration of octreotide for management of postoperative high-flow chylothorax. Ann Vasc Surg 2007 Jan;21(1):90-2
6. Octreotide LAR for severe obscure-overt gastrointestinal haemorrhage in high-risk patients on anticoagulation therapy. Gut 2007 Mar;56(3):447