PA1229 MAPK8 antigen
see all 14 MAPK8 products
10 µg / US$ 225
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Human MAPK8
Synonyms
JNK1, JNK-46 PRKM8, SAPK, JNK-1, MAPK-8, , Mitogen-activated protein kinase 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
Product review
Please read our product review about MAPK8: Antibodies to MAP-Kinases.
Product Description
Human MAPK8
Properties
| Presentation | Purified |
| Species | Human |
| Purity | >90% |
| Source | E. coli |
| Catalog Number | PA1229 |
| Swiss Prot. No. | P45983 |
| Quantity | 10 µg |
| Price | US$ 225 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA1229.pdf |
Datasheet Extract
| Recombinant Human Protein Tyrosine Phosphatase 1B (PTP-1B) | |
| Alternate names | Tyrosine-protein phosphatase non-receptor type 1, EC 3.1.3.48, Protein-tyrosine phosphatase 1B, PTP-1B, PTPN1, PTP1B |
| Concentration | 1,0 mg/ml |
| Background | Protein Tyrosine Phosphatase 1B is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. |
| Immunogen | Swiss Num.: P45983 |
| Source | Escherichia Coli |
| Format | State: Liquid purified protein (Sterile filtered colorless solution) Purity: Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE. BufferSystem: 25mM Tris-HCl, pH 7.5, 2mM b-mercaptoethanol, 1mM EDTA, 1mMDTT and 20% Glycerol |
| Description | Protein Tyrosine Phosphatase 1B Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain conjtaining 321 amino acids. AASequence: memekefeqi dksgswaaiy qdirheasdf pcrvaklpkn knrnryrdvs pfdhsriklhqedndyinas likmeeaqrs yiltqgplpn tcghfwemvw eqksrgvvml nrvmekgslkcaqywpqkee kemifedtnl kltlisedik syytvrqlel enlttqetre ilhfhyttwpdfgvpespas flnflfkvre sgslspehgp vvvhcsagig rsgtfcladt clllmdkrkdpssvdikkvl lemrkfrmgl iqtadqlrfs ylaviegakf imgdssvqdq wkelshedle pppehipppprppkrilephn Specific Activity: 10,000 U/mg (One unit will hydrolyze 1nanomole of p-nitrophenylphosphatate per minute at pH 7.4 at 37°C using 10mM of substrate) Molecular weight: 37.3 kDa |
| Storage | Store the protein undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Shelf life: one year from despatch. |