PA1281X Calcipressin-1 antigen
see all 11 Calcipressin-1 products
0.25 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Cobra Calcipressin-1
Synonyms
Venum Factor Anticomplementary Protein, RCAN1, ADAPT78, CSP1, DSC1, DSCR1, Regulator of calcineurin 1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Adapt78, Calcipressin1,
Product Description
Cobra Calcipressin-1
Properties
| Presentation | Purified |
| Species | Cobra |
| Purity | >90% |
| Source | Naja melanoleuca |
| Molecular Weight | 150 kD |
| Catalog Number | PA1281X |
| Swiss Prot. No. | P53805 |
| Quantity | 0.25 mg |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  PA1281X.pdf |
Datasheet Extract
| Alternate names | Calcipressin-1, Regulator of calcineurin 1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Adapt78, RCAN1, ADAPT78, CSP1, DSC1, DSCR1, RCN1 |
| Concentration | 1,0 mg/ml |
| Background | DSC1 encoded by a gene located in the human chromosome 21, interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. DSC1 is located in the minimal candidate region for the Down syndrome phenotype, and is over expressed in the brain of Down syndrome fetuses. Chronic over expression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. DSCR1 Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A, possibly affecting central nervous system development. |
| Immunogen | Swiss Num.: P53805 |
| Source | E.Coli |
| Format | State: Liquid purified protein (Sterile Filtered colorless solution) Purity: Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. BufferSystem: 20mM Tris-HCl pH-7.5, 100mM NaCl and 1mM DTT |
| Description | DSC1 Isoform-b Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids. AASequence: MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGPGEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS Molecular weight: 13 kDa |
| Storage | Store the protein undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
