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PA271  BRAK antigen


see all 6 BRAK products
5 µg / US$ 255
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Human BRAK

Product Description

Human BRAK

Properties

SpeciesHuman
Purity>98%
SourceE. coli
Molecular Weight9.4 kD
Catalog NumberPA271
Quantity5 µg
PriceUS$ 255
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
PA271.pdf

Datasheet Extract

Alternate namesBreast and Kidney-expressed chemokine, CXCL14, bolekine, NJAC
BackgroundBreast and Kidney-expressed chemokine (BRAK) is a CXC chemokine expressed in normal tissue in the absence of inflammatory stimuli, and infrequently expressed in cancer cell lines. BRAK is known to be a highly selective monocyte chemoattractant. However, main function and receptor selectivity is unknown at this time. BRAK contains the four highly conserved cysteine residues present in CXC chemokines. The sequence of the mature protein consists of 87 amino acid residues, and is approximately 30% homologous to the sequences of MIP-2 alpha and beta.
SourceE. coli
Format
State: Sterile filtered through a 0.2 micron filter and lyophilized
Purity: Greater than 98 % by SDS-PAGE and HPLC analyses


Endotoxinlevel: < 0.1 ng per µg (1 EU/µg)
Reconstitution: Centrifuge the vial prior to opening. Restore in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for one week or at -20°C for future use.

DescriptionRecombinant human BRAK is a 9.4 kDa polypeptide containing 77 amino acid residues.


AASequence: SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE


Biological Activity: Determined by its ability to chemoattract activated monocytes using a concentration range of 1.0 - 10.0 ng/ml.
StorageThe lyophilized protein is stable at -20°C for one year from despatch.
Reconstituted BRAK is stable for three months when stored in working aliquots with a carrier protein at -20°C.
Avoid repeated freezing and thawing.