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SM1926A  CD322 / JAM2 / JAMB antibody

see related secondary antibodies
see all 25 CD322 / JAM2 / JAMB products
1.0 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Rat anti CD322 / JAM2 / JAMB CRAM-18 F26

Synonyms

JAM2, C21orf43, VEJAM, JAM-B, JAM-2, Junctional adhesion molecule 2, , VE-JAM, CD322 antigen, Junctional adhesion molecule B, Vascular endothelial junction-associated molecule

Product Description

Rat anti CD322 / JAM2 / JAMB CRAM-18 F26, Presentation: Azide Free. Product is tested for Frozen sections ( C ), Flow cytometry ( F ), Functional assay ( FN )

Properties

ApplicationsFrozen sections ( C ), Flow cytometry ( F ), Functional assay ( FN )
ReactivityMouse ( Ms )
PresentationAzide Free
HostRat
IsotypeIgG2a
CloneCRAM-18 F26
Catalog NumberSM1926A
Swiss Prot. No.Q9JI59
Quantity1.0 mg
Priceplease contact our distributor
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
SM1926A.pdf

Datasheet Extract

Concentration1.0 mg/ml
BackgroundJAM-2 is a 45kD transmembrane type 1 protein, a member of the immunoglobulin superfamily otherwise known as CD322. In adult murine tissue, CD322 expression is reported to be restricted to high endothelial venules of lymphoid organs, lymphoendothelial cells and endothelial cells in kidney. In humans, CD322 expression is not restricted to endothelial cells, but is also expressed on human lymphocytes.
ImmunogenRecombinant soluble JAM-2. Spleen cells from immunised Fischer rats were fused with cells of the Sp2/0 myeloma cell line.
Swiss Num.: Q9JI59
Format
State: Liquid purified IgG
Purification: Affinity chromatography on Protein G
BufferSystem: PBS, pH7.4
ApplicationsFlow Cytometry: 1/10 - 1/25; Use 10µl of the suggested working dilution to label 10e6 cells in 100µl.
Immunohistochemistry on frozen sections.
Functional Assays.
SpecificityThis antibody recognises junctional adhesion molecule-2 (JAM-2). Clone CRAM-18 F26 has been reported to inhibit transendothelial migration.
Species: Mouse, Human.
StorageStore the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References1. Aurrand-Lions, M. et al. (2001) Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members. Blood. 98: 3699 - 3707.
2. Johnson-Léger, C.A. et al. (2002) Junctional adhesion molecule - 2 (JAM-2) promotes lymphocyte transendothelial migration. Blood. 100: 2479 - 2486.
3. Aurrand-Lions, M. et al. (2001) JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells. J. Biol. Chem. 276: 2733 - 2741.

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1371B Rat IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 295
   
R1371F Rat IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1371T Rat IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1371TR Rat IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1371HRP Rat IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1371AP Rat IgG (H&L)  
  Rabbit AP   1 mg / US$ 335
   
R1439C2 Rat IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1439C3 Rat IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1439C35 Rat IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1439C5 Rat IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1439C55 Rat IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1413R Rat IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Ms, Rb, Sh  
  Goat PE   1 ml / US$ 455
   
R1428R Rat IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   
R1415R Rat IgG F(ab')2 F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'SM1926A CD322 / JAM2 / JAMB'.