SP4111P Dopamine D1 Receptor / DRD1 (cytoplasm. Dom) antibody
see related secondary antibodiessee all 19 Dopamine D1 Receptor / DRD1 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti Dopamine D1 Receptor / DRD1
Synonyms
DRD1, DADR, D1R, , D(1A) dopamine receptor
Product review
Please read our product review about Dopamine D1 Receptor / DRD1 : Antibodies to Dopamine, Dopamine- hydroxylase (DBH), Dopamine-transporter and -receptors.
Product Description
Rabbit anti Dopamine D1 Receptor / DRD1 , Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Paraffin Sections ( P )
Properties
| Applications | Immunofluorescence ( IF ), Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4111P |
| Swiss Prot. No. | P21728 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4111P.pdf |
Datasheet Extract
| Alternate names | d1 dopamine receptor, d1a dopamine receptor, d1a receptor, dopamine 1 receptor, dopamine d1 receptor |
| Concentration | 1.0 mg/ml |
| Background | Dopamine Receptor D1 mediates the effect of the neurotransmitter dopamine, an intermediate in the biosynthesis of noradrenaline and adrenaline. It is involved in the control of motor activity and cognitive memory. Downregulation of DRD1 leads to severe impairments in working memory and to locomotor hyperactivity, which are observed in diseases such as schizophrenia, Parkinson's disease, affective disorders, and attention deficit hyperactivity disorder. DRD1 enhances smooth muscle contraction and vasodilation in the heart. It also modulates sodium transport in the kidney and is involved in the pathogenesis of hypertension.
Dopamine receptor D1 has been reported mostly in various regions of the brain. ESTs have been isolated from normal olfactory epithelium and cancerous genitourinary tract libraries. |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: 3rd cytoplasmic domain of human Genename: DRD1 Swiss Num.: P21728 Remarks: The immunizing peptide shows 93 % identity (93 % similarity) with mouse and 86 % identity (93 % similarity) with rat. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Immunohistochemistry with formalin fixed paraffin embedded tissues: 8 µg/ml
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Reacts with Dopamine Receptor D1 (family: GPCR; subfamily: Dopamine). Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP4111P Dopamine D1 Receptor / DRD1 '.
