SP4133P Estrogen-Related Receptor gamma antibody
see related secondary antibodiessee all 7 Estrogen-Related Receptor gamma products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti Estrogen-Related Receptor gamma -
Synonyms
ESRRG ERRG2 ERR3 NR3B3
Product review
Please read our product review about Estrogen-Related Receptor gamma : Antibodies to Estrogen Related Receptors (ERR alpha, -beta, and -gamma).
Product Description
Rabbit anti Estrogen-Related Receptor gamma -, Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4133P |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4133P.pdf |
Datasheet Extract
| Polyclonal Antibody to Human Estrogen-Related Receptor Gamma (ERR Gamma/NR3B3) | |
| Alternate names | FLJ16023, KIAA0832, DKFZP781L1617, ERR3, ERRG2, err3, errgamma, esrrg, estrogen receptor-related receptor gamma, nr3b3 |
| Concentration | 1 mg/ml |
| Background | Estrogen receptor-related receptor (ERR gamma), a NR3 Steroid Receptor, has been suggested to affect differentiation of the brain, heart, and kidney. ERR gamma binds as a monomer to an extended half-site of the ERRE type (TCAAGGTCA). ERR gamma has been shown to interact with PGC-1 alpha and has been implicated in the regulation of mitochondrial energy metabolism. In humans, ERR gamma pre-mRNA undergoes extensive alternative splicing at the 5 end, yielding at least six mRNA splice variants and two protein isoforms that differ by 23 amino acids in the N terminus. ERR gamma has been shown to be overexpressed in breast tumors, and its expression is correlated with levels of ErbB4, a likely indicator of preferred clinical course. As a result, ERR gamma has been suggested to be a potential biomarker for favorable clinical course and, possibly, hormonal sensitivity, and as a candidate target for therapeutic development.
ERR gamma expression at the mRNA and protein levels is isoform- and tissue-specific in humans. ERR gamma expression has been documented in human heart, brain, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, and small intestine. ESTs have been isolated from human tissue libraries, including cancerous fetus, uterus, lung, breast, head/neck, colon, skin, eye, adrenal, normal placenta, kidney, brain, pineal, ear, and heart. |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: near N-terminus of human Genename: ESRRG Remarks: The immunizing peptide shows 100 % identity (100 % similarity) with mouse and 100 % identity (100 % similarity) with rat. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Immunohistochemistry with formalin fixed paraffin embedded tissues: 34 µg/ml
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Reacts with Estrogen-Related Receptor Gamma
(Family: NHR, subfamily: NR3 Steroid receptor) Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of Breast cancer using anti- ESRRG antibody SP4133P |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / 170,00 € | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / 160,00 € | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / 160,00 € | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / 170,00 € | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / 170,00 € | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / 200,00 € | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 320,00 € | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 320,00 € | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / 320,00 € | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 320,00 € | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / 320,00 € | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 330,00 € | |||||
Click here to see all secondary antibodies for 'SP4133P Estrogen-Related Receptor gamma '.
