SP4371P EDG-2 / LPA1 antibody
see related secondary antibodiessee all 15 EDG-2 / LPA1 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti EDG-2 / LPA1 -
Synonyms
EDG2, LPA-1, LPAR1, vzg1, MREC1.3, REC1.3, , Lysophospholipid receptor A1, Lysophosphatidic acid receptor 1, Lysophosphatidic acid receptor Edg-2
Product review
Please read our product review about EDG-2 / LPA1 : Antibodies to Endothelial Differentiation Gene Receptors (EDG-1,-2,-4,-5,-6,-7 and -8).
Product Description
Rabbit anti EDG-2 / LPA1 -, Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4371P |
| Swiss Prot. No. | Q92633 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4371P.pdf |
Datasheet Extract
| Polyclonal Antibody to Lysophosphatidic Acid Receptor Edg2/LPA1 | |
| Alternate names | GPCR26, LPA-1, LPAR1, MREC1.3, REC.1.3, VZG-1, edg-2, endothelial differentiation gene 2, lpa1, rec.1.3, ventricular zone gene 1, vzg-1 |
| Concentration | 1 mg/ml |
| Background | Edg2, a Lysophospholipid/Lysosphingolipid Receptor, mediates growth factor-like activities such as proliferation, platelet aggregation, and chemotaxis. Edg2 is involved in myelin formation or maintenance. It is activated by platelet-derived lysophosphatidic acid (LPA), a lipid metabolite present in serum that acts ubiquitously. Although alternate translation start codons and polyadenylation sites have been reported, the alternative splicing transcripts each encode identical proteins.
Edg2 has been reported in most human tissues, and is especially abundant in brain cortical regions. ESTs have been isolated from bone, brain, breast, connective tissue, embryo, heart/melanocyte/uterus, lung, prostate, and uterus libraries. |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: 3rd cytoplasmic domain of human Genename: EDG2 Swiss Num.: Q92633 Remarks: The immunizing peptide shows 100 % identity (100 % similarity) with mouse and 100 % identity (100 % similarity) with rat. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Immunohistochemistry on paraffin embedded sections: 2-3 µg/ml
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Detects Lysophosphatidic Acid Receptor Edg2/LPA1
(Family: GPCR, Subfamily: Lysophospholipid/Lysosphingolipid) Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of Brain (Neuron and Glia) using anti- EDG2 antibody SP4371P |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP4371P EDG-2 / LPA1 '.