SP4399P mGluR3 / GRM3 (N-term) antibody
see related secondary antibodiessee all 15 mGluR3 / GRM3 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti mGluR3 / GRM3
Synonyms
Metabotropic glutamate receptor 3, GPRC1C, MGLUR3, ,
Product review
Please read our product review about mGluR3 / GRM3: Metabotropic Glutamate Receptor Antibodies.
Product Description
Rabbit anti mGluR3 / GRM3 , Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4399P |
| Swiss Prot. No. | Q14832 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4399P.pdf |
Datasheet Extract
| Alternate names | MGLU3, MGLUR3, GLUR3, GPRC1C, grm3, metabotropic glutamate receptor type 3, mGlu2/3, mGlu2/3 receptor, mGlu3, mGlu3 receptor, mGluR2/3, mGluR3, type 3 metabotropic glutamate receptor |
| Concentration | 1.0 mg/ml |
| Background | The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade.
GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3). |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: N-terminal extracellular domain of human Genename: GRM3 Swiss Num.: Q14832 Remarks: The immunizing peptide shows 88 % identity (94 % similarity) with mouse and 94 % identity (94 % similarity) with rat. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Western Blot.
Immunocytochemistry. Immunohistochemistry with formalin fixed paraffin embedded tissues: 9 µg/ml Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Reacts with Metabotropic Glutamate Receptor 3
(family: GPCR, subfamily: Metabotropic glutamate) Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of Brain (Neurons and glia) using anti- GRM3 antibody SP4399P |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP4399P mGluR3 / GRM3'.
