SP4505P Tachykinin Receptor 1 (extracell. Dom.) antibody
see related secondary antibodiessee all 6 Tachykinin Receptor 1 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti Tachykinin Receptor 1 (extracell. Dom.)
Product Description
Rabbit anti Tachykinin Receptor 1 (extracell. Dom.) , Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4505P |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4505P.pdf |
Datasheet Extract
| Alternate names | Neurokinin 1 receptor, Neurokinin receptor 1, nk-1 receptor, nk1 tachykinin receptor, nk1r, substance-p receptor |
| Concentration | 1 mg/ml |
| Background | Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis. Two variants of the tachykinin receptor 1 are produced by alternative splicing.
Tachykinin receptor 1 has been reported primarily in brain, and in blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries. Ligand: Substance P, Hemokinin 1 |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: 2nd extracellular domain of human |
| Format | State: Liquid Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide as preservative |
| Applications | Immunohistochemistry with formalin fixed paraffin embedded tissues: 2-4 µg/ml.
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | This antibody reacts with human Tachykinin Receptor 1 (Family: GPCR; Subfamily: Tachykinin).
The immunizing peptide shows 81% identity (88% homology) with mouse. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody at 4°C for one month or at -70°C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of brain (neurons and glia) using anti-TACR1 antibody |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP4505P Tachykinin Receptor 1 (extracell. Dom.)'.
