SP4662P EDG-8 / S1P5 / S1PR5 (Extracell. Dom) antibody
see related secondary antibodiessee all 7 EDG-8 / S1P5 / S1PR5 products
50 µg / no delivery possible
please contact the manufacturer
Quick Overview
Rabbit anti EDG-8 / S1P5 / S1PR5 (Extracell. Dom) -
Synonyms
EDG8 SPPR-1 SPPR1 endothelial differentiation, sphingolipid G-protein-coupled receptor 8, Endothelial differentiation G-protein-coupled receptor 8, Sphingosine 1-phosphate receptor Edg-8
Product review
Please read our product review about EDG-8 / S1P5 / S1PR5 (Extracell. Dom): Antibodies to Endothelial Differentiation Gene Receptors (EDG-1,-2,-4,-5,-6,-7 and -8).
Product Description
Rabbit anti EDG-8 / S1P5 / S1PR5 (Extracell. Dom) -, Presentation: Aff - Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP4662P |
| Swiss Prot. No. | Q9H228 |
| Quantity | 50 µg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP4662P.pdf |
Datasheet Extract
| Polyclonal Antibody to Human Sphingolipid Receptor Edg8/S1P5 | |
| Alternate names | S1PR5, SPPR-1, SPPR-2, g protein-coupled receptor edg-8, S1P(5) receptor, sphingolipid g-protein-coupled receptor 8 |
| Concentration | 1 mg/ml |
| Background | Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing.
Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1. Ligand: Sphingosine-1-Phosphate. |
| Immunogen | Synthetic peptide - KLH conjugated
Epitope: 2nd cytoplasmic domain of human Genename: EDG8 Swiss Num.: Q9H228 Remarks: The immunizing peptide shows 83 % identity (88 % similarity) with mouse and 83 % identity (88 % similarity) with rat. |
| Format | State: Liquid Ig fraction Purification: Peptide immunogen affinity column BufferSystem: PBS, pH 7.7, containing 0.01% sodium azide |
| Applications | Immunohistochemistry with formalin fixed paraffin embedded tissues: 4-21 µg/ml
Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. |
| Specificity | Reacts with Sphingolipid Receptor Edg8/S1P5
(family: GPCR; subfamily: Lysophospholipid/Lysosphingolipid) Species: Human. |
| Add. Information | This product was originally produced by MBL International. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -70°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Immunohistochemical staining of Brain (Neuron and Glia) using anti- EDG8 antibody SP4662P |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP4662P EDG-8 / S1P5 / S1PR5 (Extracell. Dom)'.
