SP5201P Estrogen-Related Receptor alpha / ESRRA antibody
see related secondary antibodiessee all 11 Estrogen-Related Receptor alpha / ESRRA products
0.1 mg / US$ 455
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Estrogen-Related Receptor alpha / ESRRA -
Synonyms
ESRRA ERR1 ERR-alpha ESRL1 NR3B1 Steroid Hormone Receptor ERR1, Estrogen receptor-like 1, Nuclear receptor subfamily 3 group B member 1
Product review
Please read our product review about Estrogen-Related Receptor alpha / ESRRA: Antibodies to Estrogen Related Receptors (ERR alpha, -beta, and -gamma).
Product Description
Rabbit anti Estrogen-Related Receptor alpha / ESRRA -, Presentation: Aff - Purified. Product is tested for Westernblot / Immunoblot ( WB )
Properties
| Applications | Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP5201P |
| Swiss Prot. No. | P11474 |
| Quantity | 0.1 mg |
| Price | US$ 455 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP5201P.pdf |
Datasheet Extract
| Polyclonal Antibody to ERR1 | |
| Concentration | 1.0 mg/ml |
| Background | Estrogen-related receptor alpha 1 (ERR alpha, ERR1) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor.
This protein binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-tnaaggtca-3' can bind to the medium-chain acyl coenzyme a dehydrogenase (mcad) response element nrre-1 and may act as an important regulator of mcad promoter. Studies have shown that ERR1 functions a metabolic regulator and is often expressed in tissues that preferentially metabolize fatty acids. The corresponding gene for the ERR1 is NR3B1. |
| Immunogen | Synthetic Peptide: M(1) S S Q V V G I E P L Y I K A E(16) corresponding to amino acid residues 1-16 from human ERR1 protein. This immunizing peptide (SP5201CP) can be used for Neutralization and control experiments. Swiss Num.: P11474 Remarks: This sequence is completely conserved between canine, human, mouse and rat. |
| Format | State: Liquid purified Ig fraction Purification: Affinity chromatography. BufferSystem: PBS with 0.05% sodium azide as preservative and 1 mg/ml BSA as stabilizer. |
| Applications | Western blot: 2 µg/ml, detects an ~52 kDa protein representing ERR1 from COS-7 transfected cells. An unidentified band is seen at ~37 kDa.
Immunohistochemistry (Paraffin): 1/100. |
| Specificity | SP5201P detects human ERR1 from transfected cells and shows no cross-reactivity to ERR3. |
| Storage | Store the antibody at -20°C.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Int. J. Cancer: 120, 2325-2330 (2007)
|
| Pictures | Figure 1. Western blot of over expressed ERR1 in COS-7 cells using SP5201P. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP5201P Estrogen-Related Receptor alpha / ESRRA'.
