Rabbit anti Estrogen-Related Receptor gamma / ESRRG SP5203P - antibody, protein, elisa from Acris Antibodies ...

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0.2 mg / US$ 455

NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Rabbit anti Estrogen-Related Receptor gamma / ESRRG

ERRG2, ERR gamma-2, ERR3, NR3B3, KIAA0832, , , Estrogen-related receptor gamma, Nuclear receptor subfamily 3 group B member 3, ERR gamma

Product review
Please read our product review about Estrogen-Related Receptor gamma / ESRRG : Antibodies to Estrogen Related Receptors (ERR alpha, -beta, and -gamma).

Rabbit anti Estrogen-Related Receptor gamma / ESRRG , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )


Alternate names	ESRRG, ERRG2, ERR3, NR3B3
Concentration	1.0 mg/ml
Background	Estrogen-related receptor gamma (ERR gamma, ERR3, NR3B3) is an orphan member of the nuclear hormone receptor superfamily. All the ERR family members (1,2, and 3) share an almost identical DNA-binding domain, which has 68% amino acid identity with that of estrogen receptor. Studies involving the crystal structure of the LBD have shown a complex between ERR3 and SRC-1. ERR3 binds as a homodimer to direct repeats (5'-AGG TCA-3'), to extended half-sites, and to the inverted estrogen response element. The corresponding gene for the ERR3 is NR3B3.
Immunogen	Synthetic peptide corresponding to residues D(401) Y E A G Q H M E D P R R(413) of human ERR3. This immunizing peptide (SP5203CP) can be used for neutralization and control experiments. *Swiss Num.:* P62508 *Remarks:* This sequence is completely conserved between human, mouse and rat.
Format	*State:* Liquid purified Ig fraction. *Purification:* Affinity chromatography. *BufferSystem:* PBS, containing 1 mg/ml BSA and 0.05% sodium azide.
Applications	Suitable for Western blot: 2 µg/ml, detects an ~54 kDa protein representing ERR1 from COS-7 transfected cells.
Specificity	SP5203P detects human ERR3 from transfected cells and shows no cross-reactivity to ERR1.
Storage	Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
References	1. Endocrinology, doi: 10.1210/me. 2005-0252, Feb 2006

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