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SP5312P  N-CoR antibody

see related secondary antibodies
see all 14 N-CoR products
50 µg / US$ 455
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Rabbit anti N-CoR

Product Description

Rabbit anti N-CoR , Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )

Properties

ApplicationsWestern blot / Immunoblot ( WB )
ReactivityMouse ( Ms )
PresentationAff - Purified
HostRabbit
Catalog NumberSP5312P
Quantity50 µg
PriceUS$ 455
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
SP5312P.pdf

Datasheet Extract

Concentration0.7 mg/ml
BackgroundSteroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcription activity of the nuclear receptor with which they associate. Silencing mediator of retinoic acid & thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR) are related transcriptional corepressors which contain two distinct domains capable of interacting with unliganded nuclear receptors to repress their basal transcriptional activity.
ImmunogenSynthetic Peptide: C P(2437) A P L L S A Q Y E T L S D S D D(2453) to amino acid residues 2437-2453 from mouse N-CoR.
Remarks: SP5312P immunizing peptide (SP5312CP) is available for use in Neutralization and Control experiments.
Format
State: Liquid purified IgG fraction.
Purification: Epitope affinity chromatography.
BufferSystem: PBS with 1 mg/ml BSA as stabilizer and 0.05% sodium azide as preservative.
ApplicationsWestern Blot: 1 µg/ml, detects a protein representing N-CoR from HeLa cell extracts.
SpecificitySP5312P detects human nuclear receptor corepressor (N-CoR).
StorageStore the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References1. Human Mol. Gen., 10(17): 1729-1740, 2001
2. Nat. Genet., 19:187-191, 1998.
3. Nat. Review Genet., 1:11-19, 2000.
4. Nature 437:759-763, 2005.
5. J. Clin. Invest. Vol. 115, No. 8, 2244-2256, 2005.

12 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1364B Rabbit IgG (H&L)  
  Goat Biotin   2 mg / US$ 295
   
R1364F Rabbit IgG (H&L)  
  Goat FITC   2 mg / US$ 285
   
R1364T Rabbit IgG (H&L)  
  Goat TRITC   2 mg / US$ 285
   
R1364TR Rabbit IgG (H&L)  
  Goat Texas Red   2 mg / US$ 295
   
R1364HRP Rabbit IgG (H&L)  
  Goat HRP   2 mg / US$ 295
   
R1364AP Rabbit IgG (H&L)  
  Goat AP   1 mg / US$ 325
   
R1458C2 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1458C3 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1458C35 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1458C5 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1458C55 Rabbit IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1427R Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'SP5312P N-CoR'.