SP5484P CaSR / PCAR1 antibody
see related secondary antibodiessee all 19 CaSR / PCAR1 products
0.1 ml / US$ 455
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti CaSR / PCAR1 -
Synonyms
Calcium Sensing Receptor, GPRC2A, PCAR1, FHH, NSHPT, , Extracellular calcium-sensing receptor, Parathyroid Cell calcium-sensing receptor
Product review
Please read our product review about CaSR / PCAR1 : Antibodies to Calcium Sensing Receptor (CaSR).
Product Description
Rabbit anti CaSR / PCAR1 -, Presentation: Aff - Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | SP5484P |
| Swiss Prot. No. | P41180 |
| Quantity | 0.1 ml |
| Price | US$ 455 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP5484P.pdf |
Datasheet Extract
| Polyclonal Antibody to// Calcium Sensing Receptor (CaSR) | |
| Alternate names | CaSR |
| Concentration | 1.4 mg/ml |
| Background | The calcium sensing receptor (CaSR) has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. Based on sequence analysis of cDNA clones it appears that the CaSR is similar to the 7-transmembrane-domain G-protein-coupled receptor superfamily. Changes in extracellular calcium are thought to modulate a balance between proliferation and differentiation in a variety of cell types. In normal primary keratinocytes and breast epithelial cells, proliferation is inhibited and elevated extracellular calcium levels trigger differentiation. Malignant transformations of these cell types are accompanied by a loss of responsiveness to the anti-proliferative effects of elevated extracellular calcium. Several disorders of calcium homeostasis have been linked to mutations in the CaSR. These include familial hypocalciuric hypercalcemia (FHH), neonatal severe hyperparathyroidism (NSHPT), and autosomal dominant hypocalemia (ADHypo). |
| Immunogen | Synthetic peptide. Swiss Num.: P41180 AA Sequence: A(12) L A W H S S A Y G P D Q R A Q(27) of rat CaSR. Remarks: This peptide (SP5484CP) is available for use in neutralization and control experiments |
| Format | State: Liquid purified Ig fraction Purification: Epitope affinity chromatography. BufferSystem: PBS containing 0.05% Sodium Azide as preservative. |
| Applications | Western Blot: 1/100, detects an ~120 kDa protein representing CaSR from HEK393 cells and rat brain homogenate. |
| Specificity | SP5484P detects calcium sensing receptor (CaSR) from human and rat tissues. Species: Human and rat. |
| Storage | Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid Freeze/Thaw Cycles. Shelf life: One year from despatch. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP5484P CaSR / PCAR1 '.