SP7189P CD267 / TACI antibody
see related secondary antibodiessee all 19 CD267 / TACI products
0.1 mg / US$ 405
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti CD267 / TACI
Synonyms
TNFRSF13B, TACI, CD267, , Transmembrane activator and CAML interactor, Tumor necrosis factor receptor superfamily member 13B
Product Description
Rabbit anti CD267 / TACI , Presentation: Purified. Product is tested for Flow cytometry ( F ), Western blot / Immunoblot ( WB )
Properties
| Applications | Flow cytometry ( F ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | SP7189P |
| Swiss Prot. No. | O14836 |
| Quantity | 0.1 mg |
| Price | US$ 405 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  SP7189P.pdf |
Datasheet Extract
| Concentration | 0.5 mg/ml |
| Background | Simultaneously four different laboratories identified a a new member of the tumor necrosis factor (TNF) family. This has been named as TALL-1 (1), THANK (TNF homologue that activates apoptosis, nuclear factor-kappaB, and c-Jun NH2-terminal kinase (2), BAFF (for B cell activating factor belonging to the TNF family) (3) and BlyS (B lymphocyte stimulator) (4). Membrane-bound BAFF is processed and secreted through the action of a protease whose specificity matches that of the furin family of proprotein convertases. The receptor for BlyS/BAFF appears to be expressed predominantly on B cells and activated T cells (5). Recently two orphan receptors TACI (6) and BCMA (,8) have been shown to be receptors for BlyS/BAFF (6-9). TACI is expressed on B cells and signals through CAML, activating the transcription factors NF-AT, NF-kB, and AP-1. TACI is a type III transmembrane protein, as defined by the lack of a cleaved signal sequence and its N-terminal extracellular exposure. The cDNA codes for 293 amino acids with predicted molecular weight of approximately 32 kDa. |
| Immunogen | Synthetic peptide corresponding to amino acids 116-132 of human TACI. Swiss Num.: O14836 Remarks: Human and mouse TACI amino acid sequences are 65% conserved in the immunogen. |
| Format | State: Liquid Ig fraction Purification: Protein G Chromatography BufferSystem: PBS containing 0.02% sodium azide |
| Applications | Western blot: 0.1-0.5 µg/ml.
Human spleen cells, Raw cells, or Daudi cells can be used as positive control. Flow cytometry. |
| Specificity | This antibody is specific for TACI. Species: Human, Mouse. |
| Storage | Store the antibody at 2 - 8 °C up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| References | 1. Shu HB, Hu WH, Johnson H J Leukoc Biol 65(5): 680-683 (1999).
2. Mukhopadhyay A, Ni J, Zhai Y, Yu GL, Aggarwal BB. J Biol Chem 274(23): 15978-15981 (1999). 3. Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N, Ambrose C, Lawton P, et al. J Exp Med 189(11): 1747-1756 (1999). 4. Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P, Soppet D, Charters M, Gentz R, Parmelee D, Li Y, Galperina O, et al. Science 285 (5425):260-3 (1999). 5. von Buelow GU and Bram RJ. Science 278: 138-141 (1997). 6. von Buelow GU, Russell H, Copeland NG, Gilbert DJ, Jenkins NA, Bram RJ. Mamm Genome 11: 628-632 (2000). 7. Laabi Y., et al. EMBO J 11: 3897-3904 (1992). 8. Gras M-P, et al. Int. Immunol 7: 1093-1106 (1995). 9. Marsters SA, Yan M, Pitti RM, Haas PE, Dixit VM, Ashkenazi A. Curr Biol 10(13): 785-788 (2000). |
| Pictures | Western blot analysis of 0.1 µg/ml of TACI in 10 µg/lane of Daudi lysate. A protein band of approximately 32 kDa is detected.
|
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'SP7189P CD267 / TACI'.
