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Product Description for CD141 / THBD
Properties for CD141 / THBD
| Manufacturer | Acris Antibodies GmbH |
| Quantity | 0.1 mg |
| Reactivity | Human |
| Presentation | Purified |
| Applications | Frozen sections, Flow cytometry, Western blot / Immunoblot |
| Isotype | IgG1 |
| Host | Mouse |
| Clone | 21-5D2 |
| PDF datasheet | view  |
| Shipping to | Worldwide |
Datasheet Extract
| Synonyms | Thrombomodulin, THRM, Fetomodulin |
| Swiss Prot Num | P07204 |
| Product Type | Antibodies |
| Recommended Isotype Control | SM10P (for use in human samples), AM03095PU-N |
| Storage | Store at 2-8°C up to one month, aliquot and store at -20°C for longer. Avoid repeated freeze/thaw cycles. Shelf life: One year from despatch. |
| References | Kodama S. et al. One-step sandwich enzyme immunoassay for soluble human thrombomodulin using monoclonal antibodies. Clin. Chim. Acta. 192, 191-200, 1990. Hayashi, T. and Suzuki, K. Monoclonal antibodies for human thrombomodulin which recognize binding sites for thrombin and protein C.J. Biochem., 108, 874-878, 1990. |
| Format | State: Liquid |
| Buffer System: 0.1 M Na-Phosphate buffer, pH 7.0 containing 0.5% protease-free bovine serum albumin and 0.09% sodium azide as preservative | |
| Specificity | The antibody specifically reacts with human placental Thrombomodulin (hTM). |
| Application | ELISA, Western blot. Immunohistochemistry on frozen sections. |
| Background | D141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure. |
| Concentration | 0.5 mg/ml |
Secondary Antibodies for CD141 / THBD
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / 190 Euro | |||||
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / 170 Euro | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / 160 Euro | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / 180 Euro | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / 170 Euro | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment | ||||||
| Rabbit | PE | 1 ml / 290 Euro | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment | ||||||
| Goat | PE | 1 ml / 290 Euro | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 290 Euro | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 270 Euro | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 250 Euro | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 250 Euro | |||||
