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Product Description for Cathepsin D
Properties for Cathepsin D
| Manufacturer | Acris Antibodies GmbH |
| Quantity | 50 µl |
| Reactivity | Human |
| Presentation | Purified |
| Applications | Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot |
| Isotype | IgG2b |
| Host | Mouse |
| Clone | 4G2 |
| PDF datasheet | view  |
| Shipping to | Worldwide |
Datasheet Extract
| Synonyms | CTSD, CPSD, Review 026 |
| Swiss Prot Num | P07339 |
| Immunogen | Recombinant human Cathepsin D (21-412 aa) purified from E. coli |
| Product Type | Antibodies |
| Recommended Isotype Control | SM12P, AM03110PU-N |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | Fusek, M et al., (2005) Biomed Papers 149, 43-50 Garcia,M et al., (1996) Stem Cells 14, 642-650 |
| Format | State: Liquid purified Ig fraction |
| Purification: Protein G affinity chromatography | |
| Buffer System: PBS, pH 7.4, containing 0.09% sodium azide | |
| Specificity | The antibody recognizes human Cathepsin D. Other species not tested. |
| Application | ELISA. Western blot (1:1,000 - 1:2,000). Immunohistochemistry on paraffin-embedded tissues (1:50). |
| Background | The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D. |
| Concentration | 1.0 mg/ml |
| Review | r026 Antibody Panel to Cathepsin Protease Family |
Secondary Antibodies for Cathepsin D
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / 190 Euro | |||||
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / 170 Euro | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / 160 Euro | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / 180 Euro | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / 170 Euro | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment | ||||||
| Rabbit | PE | 1 ml / 290 Euro | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment | ||||||
| Goat | PE | 1 ml / 290 Euro | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / 290 Euro | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / 270 Euro | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / 250 Euro | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / 250 Euro | |||||
