14-3-3 protein eta - NB100-65809 | acris-antibodies.com

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Product Description for 14-3-3 protein eta

Rabbit anti Bovine, Chicken, Human, Mouse, Rabbit, Rat, Sheep 14-3-3 protein eta.
Presentation: Serum
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for 14-3-3 protein eta

Product Category	Antibodies
Quantity	0.1 ml
Synonyms	FocusOn116, Protein AS1, YWHA1, YWHAH
Presentation	Serum
Reactivity	Bov, Chk, Hu, Ms, Rb, Rt, Sh
Applications	P, WB
Clonality	Polyclonal
Host	Rabbit
Isotype	IgG
Shipping to	Not USA/Canada
PDF datasheet	View Datasheet
Manufacturer	Novus Biologicals Inc.

Datasheet Extract

Immunogen	Swiss Prot Num: Q04917 Immunogen: Synthetic peptide corresponding to acetylated N-terminal sequence of sheep 14-3-3 eta.Peptide sequence: Ac.GDREQLLQRARC Genename: 7533
Antibody type	Ab
Application	Immunohistochemistry-Paraffin, Western Blot, Immunohistochemistry-Paraffin, Western Blot In WB detects a band of approximately 30kDa in HEK293 cell lysates. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections., Immunohistochemistry-Paraffin Western Blot
Background	Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation among many other functions.
Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format	Purification: Whole antisera Buffer System: 0.09% Sodium Azide Purity: Whole antisera State: Serum
Specificity	Specificity: Recognizes 14-3-3 eta in all mammals. It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple protein kinase signaling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preference for it?s different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 eta is expressed principally in the brain although it is expressed at low levels in other tissues. The protein binds alpha-synuclein, forming part of lewy bodies in parkinsons disease and has been linked to early-onset schizophrenia. The eta isoform binds both gremlin 1, which is overexpressed in human cancers, and the DAL-1/Protein 4.1B tumour suppressor. Furthermore the glucocortcoid receptor is positively regulated by 14-3-3- eta. NB100-65809 may not react with recombinant proteins that are not N-acetylated. Species: Bovine, Chicken, Human, Mouse, Rabbit, Rat, Sheep
Gene ID	7533
FocusOn and Reviews	FocusOns: Antibody Panel to Proteins of the 14-3-3 family (14-3-3 beta, 14-3-3 gamma, 14-3-3 epsilon, 14-3-3 zeta, 14-3-3 theta, 14-3-3 sigma, 14-3-3 eta) - FocusOn 116
Targets	14-3-3 protein eta antibody

Accessory Products

Proteins and/or Positive Controls

Proteins for 14-3-3 protein eta (4 products)

Catalog No.	Species	Pres.	Purity		Source
AR09102PU-L	14-3-3 protein eta (1-246, His-tag)
	Human	Purified	≥ 95		E. coli		0.5 mg / €750.00
							Acris Antibodies GmbH
AR09102PU-N	14-3-3 protein eta (1-246, His-tag)
	Human	Purified	≥ 95		E. coli		0.1 mg / €300.00
							Acris Antibodies GmbH
H00007533-Q01-10	14-3-3 protein eta
	Human				in vitro transl.		10 µg / €350.00
							Abnova Taiwan Corp.
H00007533-Q01-25	14-3-3 protein eta
	Human				in vitro transl.		25 µg / €500.00
							Abnova Taiwan Corp.

Positive controls for 14-3-3 protein eta (1 products)

Catalog No.	Species	Pres.	Purity		Source
NBL1-17950	14-3-3 eta Lysate
							0.1 mg / €370.00
							Novus Biologicals Inc.

Recommended Secondary Antibodies for 14-3-3 protein eta (6 products)

Catalog No.	Host	Clone/Iso.	Pres.		React.	Applications
R1364AP	Rabbit IgG (H+L chain) antibody
	Goat		AP
							Acris Antibodies GmbH
R1364B	Rabbit IgG (H+L chain) antibody
	Goat		Biotin
							Acris Antibodies GmbH
R1364F	Rabbit IgG (H+L chain) antibody
	Goat		FITC
							Acris Antibodies GmbH
R1364HRP	Rabbit IgG (H+L chain) antibody
	Goat		HRP
							Acris Antibodies GmbH
R1364T	Rabbit IgG (H+L chain) antibody
	Goat		TRITC
							Acris Antibodies GmbH
R1427R	Rabbit IgG F(ab)2 Fragment (H+L chain) antibody
	Donkey		PE
							Acris Antibodies GmbH

Click here to see all secondary antibodies for 14-3-3 protein eta

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