Product Description for 14-3-3 protein theta
Rabbit anti Mouse, Rat 14-3-3 protein theta.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.
Presentation: Aff - Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.
Properties for 14-3-3 protein theta
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | 14-3-3 protein T-cell, 14-3-3 protein tau, FocusOn116, Protein HS1, YWHAQ |
| Presentation | Aff - Purified |
| Reactivity | Ms, Rt |
| Applications | ICC/IF, P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Western Blot: 1/500-1/1000. Immunoflourescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200. |
| Background | It is a member of the 14-3-3 family which consists of 30 kDa proteins that are involved in multiple cell signalling pathways, regulation of cell cycle progression, cytoskeletal structure, transcription, intracellular trafficking and targeting. Protein interactions with 14-3-3 show distinct preferences for it’s different isoforms and are regulated by phosphorylation of both 14-3-3 and the bound protein. 14-3-3 tau/theta is primarily expressed in T-cells although it occurs at lower levels in the brain, heart, pancreas placenta and kidneys. It plays a role in cell cycle progression via interaction with p27(Kip1). Along with COPI, the theta isoform binds the GB1 RSR sequence involved in protein trafficking. The isoform forms a complex with Hsp60 and cellular prion protein which may be involved in prion diseases. Elevated levels of 14-3-3 tau/theta are observed in amyotrophic lateral sclerosis. 14-3-3 tau/theta also binds BCR/Abl, bacterial effector protein Tir, yes-associated protein and the FSH receptor. |
| Concentration | 1.0 mg/ml |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
| Format |
|
| Species Reactivity |
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| Specificity |
|
| Gene ID | 10971 |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for 14-3-3 protein theta (5 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR09103PU-L |
14-3-3 protein theta (1-245) |
||||||
 |
Human | Purified | ≥ 95 | E. coli |
0.5 mg /
€1,000.00
|
||
| Acris Antibodies GmbH | |||||||
| AR09103PU-N |
14-3-3 protein theta (1-245) |
||||||
|
Human | Purified | ≥ 95 | E. coli |
0.1 mg /
€390.00
|
||
| Acris Antibodies GmbH | |||||||
| NBC1-18393 |
14-3-3 protein theta |
||||||
![SDS-Page: 14-3-3 theta Protein [NBC1-18393] - 14-3-3 tau, 27 kDa (245 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/14-3-3 Tau Protein-SDS-Page-NBC1-18393-img0001.jpg) |
0.1 mg /
€390.00
|
||||||
| Novus Biologicals Inc. | |||||||
| H00010971-P01-10 |
14-3-3 protein theta |
||||||
 |
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00010971-P01-25 |
14-3-3 protein theta |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for 14-3-3 protein theta (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-17951 |
14-3-3 Lysate |
||||||
![Western Blot: 14-3-3 theta Lysate [NBL1-17951] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for YWHAQ](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/14-3-3 Lysate-Western Blot-NBL1-17951-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for 14-3-3 protein theta (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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