Product Description for ACO1 / IREB1
Rabbit anti Human, Mouse, Rat ACO1 / IREB1.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections.
Properties for ACO1 / IREB1
| Product Category | Antibodies |
|---|---|
| Quantity | 50 µg |
| Synonyms | Aconitase, Citrate hydro-lyase, Cytoplasmic aconitate hydratase, Ferritin repressor protein, IRP1, Iron regulatory protein 1, Iron-responsive element-binding protein 1 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | E, P |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | C, E, |
| Background | Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. |
| Concentration | 1 mg/ml |
| Storage | Store at -20C. Avoid freeze-thaw cycles. |
| Format |
|
| Gene ID | 48 |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for ACO1 / IREB1 (9 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR09811PU-N |
ACO1 / IREB1 (1-889, His-tag) |
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Human | Purified | > 90 % | E. coli |
50 µg /
€750.00
|
||
| Acris Antibodies GmbH | |||||||
| AR09811PU-S |
ACO1 / IREB1 (1-889, His-tag) |
||||||
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Human | Purified | > 90 % | E. coli |
10 µg /
€300.00
|
||
| Acris Antibodies GmbH | |||||||
| NBP1-50955-10 |
ACO1 / IREB1 |
||||||
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Human | Purified |
10 µg /
€340.00
|
||||
| Novus Biologicals Inc. | |||||||
| NBP1-50955-50 |
ACO1 / IREB1 |
||||||
![]() |
Human | Purified |
50 µg /
€740.00
|
||||
| Novus Biologicals Inc. | |||||||
| H00000048-P02 |
ACO1 / IREB1 |
||||||
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Human | Purified |
10 µg /
€420.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000048-P02-10 |
ACO1 / IREB1 |
||||||
![]() |
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000048-P02-25 |
ACO1 / IREB1 |
||||||
![]() |
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000048-Q01-10 |
ACO1 / IREB1 |
||||||
![]() |
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000048-Q01-25 |
ACO1 / IREB1 |
||||||
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Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for ACO1 / IREB1 (2 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00000048-T01 |
ACO1 293T Cell Transient Overexpression Lysate(Denatured) |
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0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
| NBL1-07243 |
Aconitase 1 Lysate |
||||||
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0.1 mg /
€370.00
|
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| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for ACO1 / IREB1 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||



![Western Blot: Aconitase 1 Lysate [NBL1-07243] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for ACO1](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Aconitase 1 Lysate-Western Blot-NBL1-07243-img0001.jpg)




