Product Description for AKT1 / PKB
Rabbit anti Human, Mouse, Rat AKT1 / PKB Y89.
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.
Presentation: Aff - Purified
Product is tested for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.
Properties for AKT1 / PKB
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | Akt-1, C-AKT, Protein kinase B, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase, Review 010 |
| Presentation | Aff - Purified |
| Reactivity | Hu, Ms, Rt |
| Applications | F, ICC/IF, IP, P, WB |
| Clonality | Monoclonal |
| Clone | Y89 |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Add. information | Research Areas: Cancer |
| Application | flow cytometry / FACS analysis, Immunocytochemistry, immunohistochemistry, immunoprecipitation, Western Blot, This antibody is useful for Flow cytometry / FACS analysis, Immunohistochemistry, Immunoprecipitation, Western Blot and Immunocytochemistry, flow cytometry / FACS analysis 1:20, immunohistochemistry 1:100, immunoprecipitation 1:100, Western Blot 1:5000-10000, Immunocytochemistry 1:100-250 |
| Background | Akt1/PKB alpha is a Ser/Thr protein kinase whose kinase activity plays a key role in various cellular functions, including apoptosis, glycogen synthesis, and cell growth . Akt1/PKB alpha is activated by various growth and survival factors (1). Phosphorylation on Thr308, Ser473 and Tyr474 is required for full activity. Akt1/PKB alpha inhibits apoptosis by phosphorylating and inactivating several targets, including caspase-9 (2). Akt1/PKB alpha regulates glycogen synthesis by phosphorylating and inactivating glycogen synthase kinase-3a and b (3,4). Three mammalian Akt1/PKB alpha isoforms have been identified. |
| General Readings |
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| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Format |
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| Specificity |
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| Gene ID | 207 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for AKT1 / PKB (9 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR08011PU-N |
AKT1 / PKB (Substrate) |
||||||
 |
Human | Purified | > 98 % |
0.5 mg /
€220.00
|
|||
| Acris Antibodies GmbH | |||||||
| GTX29041 |
AKT1 / PKB control peptide |
||||||
|
50 µg /
€250.00
|
||||||
| GeneTex Inc. | |||||||
| H00000207-P01-10 |
AKT1 / PKB |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000207-P01-25 |
AKT1 / PKB |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000207-Q01-10 |
AKT1 / PKB |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000207-Q01-25 |
AKT1 / PKB |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000207-Q02 |
AKT1 / PKB |
||||||
|
Human | Purified |
10 µg /
€330.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000207-Q02-10 |
AKT1 / PKB |
||||||
|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000207-Q02-25 |
AKT1 / PKB |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for AKT1 / PKB (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| NBL1-07441 |
AKT1 Lysate |
||||||
![Western Blot: AKT1 Lysate [NBL1-07441] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for AKT1](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/AKT1 Lysate-Western Blot-NBL1-07441-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for AKT1 / PKB (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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