NBP1-03433 AKT1 / PKB pSer473 antibody

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0.1 ml / €370.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

Quick Overview

Sheep anti Human, Mouse, Rat AKT1 / PKB

NBP1-03433

Product Description for AKT1 / PKB

Sheep anti Human, Mouse, Rat AKT1 / PKB.
Properties: pSer473
Presentation: Serum
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for AKT1 / PKB

Product Category Antibodies
Quantity 0.1 ml
Synonyms Akt-1, C-AKT, Protein kinase B, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase, Review 010
Presentation Serum
Reactivity Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Sheep
Shipping to Not USA/Canada
PDF datasheet View Datasheet
Manufacturer Novus Biologicals Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
P31749
Immunogen:
A synthetic peptide from the phospho S473 c-terminal of AKT (RAC-alpha serine/threonine-protein kinase, PKB, RAC) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, human and chicken AKT1.
Genename:
207
Property pSer473
Antibody type Ab
Add. information Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability.
Research Areas: Cancer
Application immunohistochemistry, Western Blot, This antibody is useful for Immunohistochemistry and Western Blot. , immunohistochemistry, Western Blot 1:300-1:2000,
Background General protein kinase capable of phosphorylating several known proteins. phosphorylates tbc1d4. signals downstream of phosphatidylinositol 3-kinase (pi(3)k) to mediate the effects of various growth factors such as platelet-derived growth factor (pdgf), epidermal growth factor (egf), insulin and insulin-like growth factor i (igf-i). plays a role in glucose transport by mediating insulin-induced translocation of the glut4 glucose transporter to the cell surface. mediates the antiapoptotic effects of igf-i. mediates insulin-stimulated protein synthesis, partly by playing a role in both insulin-induced phosphorylation of 4e-bp1 and in insulin-induced activation of p70 s6 kinase. promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.
General Readings
  • Cong L.N, et al. Mol. Endocrinol. 11:1881-1890(1997).
  • Pekarsky Y, et al. Proc. Natl. Acad. Sci. U.S.A. 97:3028-3033(2000).
  • Maira S.-M, et al. Science 294:374-380(2001).
  • Anai M, et al. J. Biol. Chem. 280:18525-18535(2005).
  • Olsen J.V, et al. Cell 127:635-648(2006).
Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Format
Purification:
Whole antisera
Buffer System:
No Preservative
Purity:
Whole antisera
State:
Serum
Specificity
Specificity:
AKT1, AKT2, AKT3. NBP1-03433 is also very likely to recognise the unphosphorylated form.
Species:
Human, Mouse, Rat
Gene ID 207
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for AKT1 / PKB (9 products)

Catalog No. Species Pres. Purity   Source  
AR08011PU-N

AKT1 / PKB (Substrate)

AKT1 / PKB Human Purified > 98 %
0.5 mg / €220.00
  Acris Antibodies GmbH
GTX29041

AKT1 / PKB control peptide

AKT1 / PKB
50 µg / €250.00
  GeneTex Inc.
H00000207-P01-10

AKT1 / PKB

AKT1 / PKB Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000207-P01-25

AKT1 / PKB

AKT1 / PKB Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00000207-Q01-10

AKT1 / PKB

AKT1 / PKB Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000207-Q01-25

AKT1 / PKB

AKT1 / PKB Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00000207-Q02

AKT1 / PKB

AKT1 / PKB Human Purified
10 µg / €330.00
  Abnova Taiwan Corp.
H00000207-Q02-10

AKT1 / PKB

AKT1 / PKB Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00000207-Q02-25

AKT1 / PKB

AKT1 / PKB Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for AKT1 / PKB (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-07441

AKT1 Lysate

Western Blot: AKT1 Lysate [NBL1-07441] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for AKT1
0.1 mg / €370.00
  Novus Biologicals Inc.