Apolipoprotein J (Apo J) (N-term) - BP5023 | acris-antibodies.com

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Product Description for Apolipoprotein J (Apo J)

Rabbit anti Human Apolipoprotein J (Apo J).
Properties: (N-term)
Presentation: Serum
Product is tested for Western blot / Immunoblot.

Properties for Apolipoprotein J (Apo J)

Product Category	Antibodies
Quantity	0.25 ml
Synonyms	40, 40, AAG4, APOJ, Aging-associated gene 4 protein, CLI, Clusterin, Complement cytolysis inhibitor, Complement-associated protein SP-40, FocusOn036, FocusOn130, KUB1, Ku70-binding protein 1, NA1/NA2, SP-40, Testosterone-repressed prostate message 2
Presentation	Serum
Reactivity	Hu
Applications	WB
Clonality	Polyclonal
Host	Rabbit
Shipping to	Worldwide
PDF datasheet	View Datasheet
Manufacturer	Acris Antibodies GmbH
Material safety datasheet	MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen	Swiss Prot Num: P10909 Immunogen: Synthetic Human clusterin peptide (N-terminal sequence DRIDSLLENDRQQTH, coupled to KLH) Genename: 1191
Property	N-term
Antibody type	Ab
Application	Immunoblotting: 1/500 (using ECL method). Positive Control: Human Serum or HDL fraction.
Background	Clusterin is a secreted glycoprotein found in many biological fluids. It is believed to protect cell membranes from damage, to participate in wound-repair processes, and its expresson might be related to tissue remodeling after cell death. Clusterin is found in many organs, elevated levels are found in the CNS under some neuropathological conditions, such as Alzheimers disease, where it is associated with amyloid-beta plaques.
General Readings	Bajari TM, Strasser V, Nimpf J, Schneider WJ. A model for modulation of leptin activity by association with clusterin. FASEB J. 2003 Aug;17(11):1505-7. Epub 2003 Jun 3. PubMed PMID: 12824284. Debure L, Vayssiere JL, Rincheval V, Loison F, Le Drean Y, Michel D. Intracellular clusterin causes juxtanuclear aggregate formation and mitochondrial alteration. J Cell Sci. 2003 Aug 1;116(Pt 15):3109-21. Epub 2003 Jun 10. PubMed PMID: 12799419. Ishikawa Y, Akasaka Y, Ishii T, Komiyama K, Masuda S, Asuwa N, et al. Distribution and synthesis of apolipoprotein J in the atherosclerotic aorta. Arterioscler Thromb Vasc Biol. 1998 Apr;18(4):665-72. PubMed PMID: 9555874. Mackness B, Hunt R, Durrington PN, Mackness MI. Increased immunolocalization of paraoxonase, clusterin, and apolipoprotein A-I in the human artery wall with the progression of atherosclerosis. Arterioscler Thromb Vasc Biol. 1997 Jul;17(7):1233-8. PubMed PMID: 9261251. Michel D, Moyse E, Trembleau A, Jourdan F, Brun G. Clusterin/ApoJ expression is associated with neuronal apoptosis in the olfactory mucosa of the adult mouse. J Cell Sci. 1997 Jul;110 ( Pt 14):1635-45. PubMed PMID: 9247197.
Storage	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Format	State: Liquid Serum Serum
Specificity	Specificity: Specific for the beta-chain of the a-subunit, according to Debure et al (Ref.1.) Detects the 43 kD band of Human Clusterin under reduced conditions. Species: Human.
Gene ID	1191
FocusOn and Reviews	FocusOns: Antibodies to Apolipoprotein - FocusOn 036
Targets	Apolipoprotein J (Apo J) antibody

Accessory Products

Recommended Secondary Antibodies for Apolipoprotein J (Apo J) (6 products)

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R1364AP	Rabbit IgG (H+L chain) antibody
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R1364F	Rabbit IgG (H+L chain) antibody
	Goat		FITC
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R1364HRP	Rabbit IgG (H+L chain) antibody
	Goat		HRP
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R1364T	Rabbit IgG (H+L chain) antibody
	Goat		TRITC
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R1427R	Rabbit IgG F(ab)2 Fragment (H+L chain) antibody
	Donkey		PE
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