Product Description for ASNS / TS11
Rabbit anti Human, Rat ASNS / TS11 EP282Y.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.
Presentation: Purified
Product is tested for Immunocytochemistry/Immunofluorescence, Paraffin Sections, Western blot / Immunoblot.
Properties for ASNS / TS11
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | Asparagine synthetase, Asparagine synthetase [glutamine-hydrolyzing], Cell cycle control protein TS11, Glutamine-dependent asparagine synthetase |
| Presentation | Purified |
| Reactivity | Hu, Rt |
| Applications | ICC/IF, P, WB |
| Clonality | Monoclonal |
| Clone | EP282Y |
| Host | Rabbit |
| Isotype | IgG |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Immunocytochemistry, immunohistochemistry, Western Blot, This antibody is useful for Immunohistochemistry, Western Blot and Immunocytochemistry, immunohistochemistry 1:50, Western Blot 1:1000-2000, Immunocytochemistry 1:50-100 |
| Background | Asparagine synthetase (AS) is a housekeeping enzyme responsible for the production of asparagine from aspartate and glutamine. Most mammalian cells express AS and regulate the level of activity in response to the concentration of asparagine in the medium. Certain tumor cells in contrast, exhibit little or no AS activity and rely on the surrounding medium as a source of exogenous asparagines (1). Therefore tumor cells may be selectively killed by a chemotherapeutic drug using asparaginase. This approach has been exploited in the treatment of certain cancers like childhood acute lymphoblastic leukemia (2). |
| General Readings | 1. Gantt, J. S., C.-S. Chiang, G. W. Hatfield, and S. M. Arfin. J. Biol. Chem. 255:4808-4813. 2. Ortega, J. A., M. E. Nesbit, Jr., M. H. Donaldson, R. H. Hittle, J. Weiner, M. Karon, and D. Hammond. 1977. Cancer Res. 37:535-540. |
| Storage | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Format |
|
| Specificity |
|
| Gene ID | 440 |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for ASNS / TS11 (4 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00000440-P01-10 |
ASNS / TS11 |
||||||
 |
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000440-P01-25 |
ASNS / TS11 |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000440-Q01-10 |
ASNS / TS11 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00000440-Q01-25 |
ASNS / TS11 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for ASNS / TS11 (3 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00000440-T01 |
ASNS 293T Cell Transient Overexpression Lysate(Denatured) |
||||||
|
0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
| NBL1-07768 |
Asparagine synthetase Lysate |
||||||
![Western Blot: Asparagine synthetase Lysate [NBL1-07768] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for synthetase.](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Asparagine synthetase Lysate-Western Blot-NBL1-07768-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
| NBL1-07770 |
Asparagine synthetase Lysate |
||||||
![Western Blot: Asparagine synthetase Lysate [NBL1-07770] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for ASNS](http://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/Novus/Asparagine synthetase Lysate-Western Blot-NBL1-07770-img0001.jpg) |
0.1 mg /
€370.00
|
||||||
| Novus Biologicals Inc. | |||||||
Recommended Secondary Antibodies for ASNS / TS11 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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