SM5121 ATP1A1 (all alpha forms) antibody

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0.4 ml / €370.00
Delivery Time: 7-10 working days

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Mouse anti Bovine, Canine, Chicken, Human, Porcine, Rat, Sheep ATP1A1 M7-PB-E9

SM5121

Product Description for ATP1A1

Mouse anti Bovine, Canine, Chicken, Human, Porcine, Rat, Sheep ATP1A1 M7-PB-E9.
Properties: (all alpha forms)
Presentation: Ascites
Product is tested for Frozen Sections, Enzyme Immunoassay, Immunoprecipitation, Western blot / Immunoblot.

Properties for ATP1A1

Product Category Antibodies
Quantity 0.4 ml
Synonyms Na(+)/K(+) ATPase alpha-1 subunit, Review 012, Sodium pump ATPase subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1
Presentation Ascites
Reactivity Bov, Can, Chk, Hu, Por, Rt, Sh
Applications C, E, IP, WB
Clonality Monoclonal
Clone M7-PB-E9
Host Mouse
Isotype IgG1
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P04074
Immunogen:
Purified alpha sodium/potassium ATPase from sheep kidney.
Genename:
443381
Property all alpha forms
Antibody type Ab
Application Immunohistochemistry: 1:100.
ELISA: Assay dependent.
Western Blot: 1:250; an ~110 kDa protein representing alpha sodium/potassium ATPase from MDCK cell extract.
Immunoprecipitation: Assay dependent.
Background The antigen is purified sheep kidney alpha sodium/potassium ATPase. The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium/potassium ATPase exhibit tissue-specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression. The alpha subunit has been found in kidney, brain, heart, and to a lesser extent liver, skeletal and smooth muscle.
Format
Purification:
Affinity chromatography on Protein A
State:
Liquid purified IgG containing 0.05% sodium azide
Ascites
Specificity
Specificity:
This antibody detects sodium/potassium ATPase alpha from. This antibody recognizes an epitope between amino acid residues 646 and 652 of the sheep kidney alpha sodium/potassium ATPase.
Species:
Canine, Mouse, Porcine, Rat, Bovine, Sheep, Human, Chicken.
Gene ID 443381
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