SM5123 ATP1B1 antibody

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0.2 ml / €370.00
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Mouse anti Canine, Human, Porcine, Sheep ATP1B1 M17-P5-F11

SM5123

Product Description for ATP1B1

Mouse anti Canine, Human, Porcine, Sheep ATP1B1 M17-P5-F11.
Presentation: Ascites
Product is tested for Frozen Sections, Immunoprecipitation, Western blot / Immunoblot.

Properties for ATP1B1

Product Category Antibodies
Quantity 0.2 ml
Synonyms Review 012, Sodium Pump ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1, Sodium/potassium-transporting ATPase subunit beta-1
Presentation Ascites
Reactivity Can, Hu, Por, Sh
Applications C, IP, WB
Clonality Monoclonal
Clone M17-P5-F11
Host Mouse
Isotype IgG2a
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
P05026
Immunogen:
Purified lamb kidney beta sodium/potassium ATPase.
Genename:
481
Antibody type Ab
Application Western Blot: 1:250; an ~42 kDa protein in liver samples and ~55 kDa in kidney samples representing beta sodium/potassium ATPase in sheep liver extract.
Immunoprecipitation.
Immunohistochemistry: 1:100.
Background The antigen is purified lamb kidney sodium/potassium ATPase beta. The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium/potassium ATPase exhibit a tissue-specific and developmental pattern of expression. The alpha 1 and beta mRNAs are present in all cell types examined whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression.
General Readings
  • J. Biol. Chem., Vol 278: 34794 - 34803, Sept 2003
  • Gut Vol 52, 1607-1615, Nov 2003
  • PNAS 99(22):14572-14577, 2002.
  • J. Biol. Chem., Dec 2006; 281: 39573 - 39587.
  • J. Biol. Chem., Feb 2001; 276: 4304 - 4314.
  • J Physiol 556.2, 507-519, Apr 2004
  • American Journal of Physiology, 262: C1491-C1499, 1992.
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid Ascites containing 0.05% sodium azide
Ascites
Specificity
Specificity:
This antibody detects sodium/potassium ATPase beta 1. This antibody recognizes and epitope between amino acid residues 195-199 of sheep sodium/potassium ATPase beta 1.
Species:
Human, Sheep, Canine, Porcine.
Gene ID 481
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for ATP1B1 (2 products)

Catalog No. Species Pres. Purity   Source  
H00000481-P01-10

ATP1B1

ATP1B1 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000481-P01-25

ATP1B1

ATP1B1 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.

Positive controls for ATP1B1 (1 products)

Catalog No. Species Pres. Purity   Source  
NBL1-07811

Sodium Potassium ATPase Beta 1 Lysate

Western Blot: Sodium Potassium ATPase Beta 1 Lysate [NBL1-07811] - Western Blot experiments. 
Left-Control; Right -Over-expression Lysate for ATP1B1
0.1 mg / €370.00
  Novus Biologicals Inc.