Product Description for ATP2A2 / SERCA2
Mouse anti Canine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat ATP2A2 / SERCA2 2A7-A1.
Presentation: Ascites
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.
Presentation: Ascites
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Paraffin Sections, Immunoprecipitation, Western blot / Immunoblot.
Properties for ATP2A2 / SERCA2
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | ATP2B, Calcium pump 2 ATPase, Calcium-transporting ATPase sarcoplasmic reticulum type, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Review 012, SR Ca(2+)-ATPase 2, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, slow twitch skeletal muscle isoform |
| Presentation | Ascites |
| Reactivity | Can, GP, Hu, Ms, Por, Rb, Rt |
| Applications | C, ICC/IF, IP, P, WB |
| Clonality | Monoclonal |
| Clone | 2A7-A1 |
| Host | Mouse |
| Isotype | IgG2a |
| Shipping to | Not USA/Canada |
| PDF datasheet | View Datasheet |
| Manufacturer | Novus Biologicals Inc. |
Datasheet Extract
| Immunogen |
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|---|---|
| Antibody type | Ab |
| Application | immunohistochemistry, immunoprecipitation, Western Blot, By Western blot, this antibody detects an ~110 kDa protein representing SERCA2 ATPase in rat cardiac tissue. It has also been used on frozen sections for histochemistry., immunohistochemistry , immunoprecipitation , Western Blot |
| Background | ATP dependent calcium pumps are responsible in part for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are comprised of a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific isoform expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells. |
| Concentration | 2.1 mg/ml |
| General Readings | Temsah RM et al. Alterations in sarcoplasmic reticulum function and gene expression in ischemic-reperfused rat heart. Am J Physiol 277:H584-94 (1999). Movsesian MA et al. Ca(2+)-transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium. Circulation 90:653-7 (1994). Liu BF et al. Consequences of functional expression of the plasma membrane Ca2+ pump isoform 1a. J Biol Chem 271:5536-44 (1996). Rockman HA et al. Molecular and physiological alterations in murine ventricular dysfunction. Proc Natl Acad Sci U S A 91:2694-8 (1994). |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Format |
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| Specificity |
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| Gene ID | 488 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Recommended Secondary Antibodies for ATP2A2 / SERCA2 (8 products)
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Rabbit | Texas Red | |||||
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| R1403R |
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Rabbit | PE | |||||
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| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Goat | PE | |||||
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| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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Donkey | PE | |||||
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