Product Description for ATP2A2 / SERCA2
Mouse anti Bovine, Canine, Human, Porcine, Rabbit, Rat ATP2A2 / SERCA2 IID8.
Presentation: Ascites
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.
Presentation: Ascites
Product is tested for Frozen Sections, Immunocytochemistry/Immunofluorescence, Western blot / Immunoblot.
Properties for ATP2A2 / SERCA2
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 ml |
| Synonyms | ATP2B, Calcium pump 2 ATPase, Calcium-transporting ATPase sarcoplasmic reticulum type, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, Review 012, SR Ca(2+)-ATPase 2, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, slow twitch skeletal muscle isoform |
| Presentation | Ascites |
| Reactivity | Bov, Can, Hu, Por, Rb, Rt |
| Applications | C, ICC/IF, WB |
| Clonality | Monoclonal |
| Clone | IID8 |
| Host | Mouse |
| Isotype | IgG1 |
| Shipping to | Worldwide |
| PDF datasheet | View Datasheet |
| Manufacturer | Acris Antibodies GmbH |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Application | Immunocytochemistry. Immunohistochemistry on Frozen Sections: 1/500. Western Blot: 1/2,500, detects an ~110 kDa protein representing SERCA2 ATPase from canine skeletal muscle triad preparations. Note: This antibody is not recommneded for Western blot detection of rat SERCA2. Immunofluorescence: Staining of SECRA2 ATPase in rabbit skeletal muscle with SM5104 results in strong labelling of the entire type I (slow) myofiber consistent with sarcoplasmic reticulum localization. |
| Background | The antigen is purified canine cardiac sarcoplasmic reticulum. ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells. |
| Concentration | 7.8 mg/ml |
| General Readings |
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| Storage | Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Format |
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| Specificity |
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| Gene ID | 488 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Recommended Secondary Antibodies for ATP2A2 / SERCA2 (8 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1253AP |
Mouse IgG (H+L chain) antibody |
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|
Rabbit | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1253B |
Mouse IgG (H+L chain) antibody |
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|
|
Rabbit | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1253F |
Mouse IgG (H+L chain) antibody |
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|
|
Rabbit | FITC | |||||
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| R1253HRP |
Mouse IgG (H+L chain) antibody |
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|
Rabbit | HRP | |||||
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| R1253TR |
Mouse IgG (H+L chain) antibody |
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|
|
Rabbit | Texas Red | |||||
| Acris Antibodies GmbH | |||||||
| R1403R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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|
|
Rabbit | PE | |||||
| Acris Antibodies GmbH | |||||||
| R1405R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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|
|
Goat | PE | |||||
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| R1455R |
Mouse IgG (H+L chain), F(ab)2 Fragment, adsorbed antibody |
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|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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