Product Description for BAG2
Rabbit anti Bovine, Canine, Chicken, Human, Mouse, Rat, Zebrafish BAG2.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.
Properties for BAG2
| Product Category | Antibodies |
|---|---|
| Quantity | 0.1 mg |
| Synonyms | BAG family molecular chaperone regulator 2, BAG-2, Bcl-2-associated athanogene 2, Review 004 |
| Presentation | Aff - Purified |
| Reactivity | Bov, Can, Chk, Hu, Ms, Rt, Ze |
| Applications | P, WB |
| Clonality | Polyclonal |
| Host | Rabbit |
| Shipping to | Europe only |
| PDF datasheet | View Datasheet |
| Manufacturer | AVIVA Systems Biology |
Datasheet Extract
| Immunogen |
|
|---|---|
| Antibody type | Ab |
| Add. information | Rabbit IgG purified by protein A chromatography. 23kDa |
| Application | Suggested dilution at 1.25 ELISA titre using peptide based assay: 1:1562500 |
| Background | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
| General Readings | Arndt,V., (2005) Mol. Biol. Cell 16 (12), 5891-5900 |
| Storage | Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 ?l of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20DegC. Avoid repeat freeze-thaw cycles. |
| Format |
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| Specificity |
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| Gene ID | 9532 |
| FocusOn and Reviews | |
| Targets |
Accessory Products
Proteins and/or Positive Controls
Proteins for BAG2 (8 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| AR09892PU-L |
BAG2 (1-211, His-tag) |
||||||
 |
Human | Purified | > 95 % | E. coli |
0.5 mg /
€750.00
|
||
| Acris Antibodies GmbH | |||||||
| AR09892PU-N |
BAG2 (1-211, His-tag) |
||||||
|
Human | Purified | > 95 % | E. coli |
0.1 mg /
€300.00
|
||
| Acris Antibodies GmbH | |||||||
| NBP1-51025-0.1 |
BAG2 |
||||||
 |
Human | Purified |
0.1 mg /
€340.00
|
||||
| Novus Biologicals Inc. | |||||||
| NBP1-51025-0.5 |
BAG2 |
||||||
|
Human | Purified |
0.5 mg /
€740.00
|
||||
| Novus Biologicals Inc. | |||||||
| H00009532-P01-10 |
BAG2 |
||||||
|
Human | Purified |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00009532-P01-25 |
BAG2 |
||||||
|
Human | Purified |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00009532-Q01-10 |
BAG2 |
||||||
|
Human | in vitro transl. |
10 µg /
€350.00
|
||||
| Abnova Taiwan Corp. | |||||||
| H00009532-Q01-25 |
BAG2 |
||||||
|
Human | in vitro transl. |
25 µg /
€500.00
|
||||
| Abnova Taiwan Corp. | |||||||
Positive controls for BAG2 (1 products)
| Catalog No. | Species | Pres. | Purity | Source | |||
|---|---|---|---|---|---|---|---|
| H00009532-T01 |
BAG2 Lysate(Denatured) |
||||||
|
0.1 ml /
€240.00
|
||||||
| Abnova Taiwan Corp. | |||||||
Recommended Secondary Antibodies for BAG2 (6 products)
| Catalog No. | Host | Clone/Iso. | Pres. | React. | Applications | ||
|---|---|---|---|---|---|---|---|
| R1364AP |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | AP | |||||
| Acris Antibodies GmbH | |||||||
| R1364B |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | Biotin | |||||
| Acris Antibodies GmbH | |||||||
| R1364F |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | FITC | |||||
| Acris Antibodies GmbH | |||||||
| R1364HRP |
Rabbit IgG (H+L chain) antibody |
||||||
|
Goat | HRP | |||||
| Acris Antibodies GmbH | |||||||
| R1364T |
Rabbit IgG (H+L chain) antibody |
||||||
|
|
Goat | TRITC | |||||
| Acris Antibodies GmbH | |||||||
| R1427R |
Rabbit IgG F(ab)2 Fragment (H+L chain) antibody |
||||||
|
|
Donkey | PE | |||||
| Acris Antibodies GmbH | |||||||
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