AP11294PU-N Bax (BH3 Domain) antibody

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0.4 ml / €340.00
Please visit the appropriate website of Acris Antibodies or contact your local Distributor to buy this product.

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Rabbit anti Human, Mouse Bax

AP11294PU-N

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  • AP11294PU-N

Product Description for Bax

Rabbit anti Human, Mouse Bax.
Properties: (BH3 Domain)
Presentation: Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for Bax

Product Category Antibodies
Quantity 0.4 ml
Synonyms Apoptosis regulator BAX, BCL2-associated X protein, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4
Presentation Purified
Reactivity Hu, Ms
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype Ig
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q07812
Immunogen:
This antibody was developed against a synthetic peptide selected from the N-terminal region (BH3 domain) of human Bax.
Genename:
581
Property BH3 Domain
Antibody type Ab
Control peptide AP11294CP-N
Add. information Calculated MW: 24220 Da
Application ELISA: 1/1,000.
Western blot: 1/100-1/500.
Immunohistochemistry: 1/50-1/100.
Background Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Caution This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Concentration lot specific
General Readings
  1. Liu, F.T., et al., Biochem. Biophys. Res. Commun. 310(3):956-962 (2003).
  2. Roucou, X., et al., J. Biol. Chem. 278(42):40877-40881 (2003).
  3. Cao, X., et al., Blood 102(7):2605-2614 (2003).
  4. McJilton, M.A., et al., Oncogene 22(39):7958-7968 (2003).
  5. Bidere, N., et al., J. Biol. Chem. 278(33):31401-31411 (2003).
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Buffer System:
PBS containing 0.09% (W/V) Sodium Azide as preservative.
State:
Liquid purified Ig fraction.
Purified
Specificity
Specificity:
This antibody is specific to Bax (BH3 Domain).
Species:
Human.
Gene ID 581
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Bax (5 products)

Catalog No. Species Pres. Purity   Source  
GTX27987

Bax Control Peptide

Bax
0.1 mg / €230.00
  GeneTex Inc.
H00000581-P01-10

Bax

Bax Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000581-P01-25

Bax

Bax Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00000581-Q01-10

Bax

Bax Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000581-Q01-25

Bax

Bax Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
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