SP1157S Bax antibody

See related secondary antibodies

Search for all "Bax"

20 µl / €190.00
Delivery Time: 3-5 working days

Quick Overview

Rabbit anti Human Bax

SP1157S

Product Description for Bax

Rabbit anti Human Bax.
Presentation: Serum
Product is tested for Immunoprecipitation, Western blot / Immunoblot, Paraffin Sections.

Properties for Bax

Product Category Antibodies
Quantity 20 µl
Synonyms Apoptosis regulator BAX, BCL2-associated X protein, BCL2L4, Bcl-2-like protein 4, Bcl2-L-4, FocusOn130, Review 004
Presentation Serum
Reactivity Hu
Applications IP, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q07812
Immunogen:
Synthetic peptide corresponding to amino acids 43-61 of human Bax.
Antibody type Ab
Application Western Blot.
Immunoprecipitation: 1/1000.
Immunohistochemistry on paraffin sections: 1/1000 - 1/2000; this product requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Recommended Positive Control: Normal Breast Tissue.
Background Bax protein is a proapoptotic member of the Bcl-2 family. BAX accelerates programmed cell death by binding to and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. It also induces the release of cytochrome C , activation of CASP3 and thereby apoptosis. Defects in BAX are found in some cell lines from hematopoietic malignancies as T-cell acute lymphoblastic leukemia, Burkitt lymphoma, and plasmacytoma.
General Readings
  • Krajewski S, Blomqvist C, Franssila K, Krajewska M, Wasenius VM, Niskanen E, et al. Reduced expression of proapoptotic gene BAX is associated with poor response rates to combination chemotherapy and shorter survival in women with metastatic breast adenocarcinoma. Cancer Res. 1995 Oct 1;55(19):4471-8. PubMed PMID: 7671262.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
State:
Liquid serum containing 0.09% Sodium Azide
Serum
Specificity
Specificity:
This antibody recognises the Bax protein. Bax migrates as a 21kD band when detected by this antibody in immunoblotting applications.
Species:
Human.
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Bax (5 products)

Catalog No. Species Pres. Purity   Source  
GTX27987

Bax Control Peptide

Bax
0.1 mg / €230.00
  GeneTex Inc.
H00000581-P01-10

Bax

Bax Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000581-P01-25

Bax

Bax Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.
H00000581-Q01-10

Bax

Bax Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00000581-Q01-25

Bax

Bax Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.