AP02775PU-S Bcl-2-like 11 antibody

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Regular Price: 50 µg / €230.00

Special Price: 50 µg / €184.00

Delivery Time: 7-10 working days

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Rabbit anti Human, Mouse Bcl-2-like 11

AP02775PU-S

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  • AP02775PU-S

Product Description for Bcl-2-like 11

Rabbit anti Human, Mouse Bcl-2-like 11.
Presentation: Aff - Purified
Product is tested for Western blot / Immunoblot, Paraffin Sections.

Properties for Bcl-2-like 11

Product Category Antibodies
Quantity 50 µg
Synonyms BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS, Review 004
Presentation Aff - Purified
Reactivity Hu, Ms
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer Acris Antibodies GmbH

Datasheet Extract

Immunogen
Swiss Prot Num:
O43521
Immunogen:
The antiserum was produced against synthesized non-phosphopeptide derived from Mouse BIM around the phosphorylation site of Serine 65 (P-A-Sp-P-G).
Genename:
10018
Antibody type Ab
Application Immunohistochemistry: 1/50~1/100.
Western Blot: 1/500~1/1000.
Background Bim, Bcl-2 interacting mediator of cell death, is a pro-apoptotic protein belonging to the Bcl2 family of proteins containing a Bcl2 homology domain 3 (BH3). It is proapoptotic and exerts its effects by interacting with prosurvival members of the Bcl2 family like Bcl2, BclxL and Bclw. Bim is sequestered in an inactive conformation through binding to the microtubule-associated dynein motor complex. Certain apoptotic stimuli release Bim from microtubules, allowing inhibitory binding to anti-apoptotic Bcl-2 family members and subsequent iniation of apoptosis.
Concentration 1.0 mg/ml
General Readings
  • Fukazawa H, et al. (2004) Mol Cancer Ther ; 3(10): 1281-1288
  • Luciano F, et al. (2003) Oncogene ; 22(43): 6785-6793
Storage Store the antibody at -20°C.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Affinity Chromatography using epitope-specific immunogen.
Buffer System:
PBS (without Mg2+ and Ca2+), pH 7.4 containing 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
State:
Liquid purified IgG fraction.
Aff - Purified
Specificity
Specificity:
BIM antibody detects endogenous levels of total BIM protein.
Species:
Human, Mouse and Rat.
Gene ID 10018
FocusOn and Reviews
Reviews:
Targets

Accessory Products

Proteins and/or Positive Controls

Proteins for Bcl-2-like 11 (7 products)

Catalog No. Species Pres. Purity   Source  
H00010018-P01-10

Bcl-2-like 11

Bcl-2-like 11 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00010018-P01-25

Bcl-2-like 11

Bcl-2-like 11 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00010018-P02

Bcl-2-like 11

Bcl-2-like 11 Human Purified
10 µg / €420.00
  Abnova Taiwan Corp.
H00010018-P02-10

Bcl-2-like 11

Bcl-2-like 11 Human Purified
10 µg / €350.00
  Abnova Taiwan Corp.
H00010018-P02-25

Bcl-2-like 11

Bcl-2-like 11 Human Purified
25 µg / €500.00
  Abnova Taiwan Corp.
H00010018-Q01-10

Bcl-2-like 11

Bcl-2-like 11 Human in vitro transl.
10 µg / €350.00
  Abnova Taiwan Corp.
H00010018-Q01-25

Bcl-2-like 11

Bcl-2-like 11 Human in vitro transl.
25 µg / €500.00
  Abnova Taiwan Corp.